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• W1847444310 startingPage "1677" @default.
• W1847444310 abstract "Abstract Genealogies from rapidly growing populations have approximate “star” shapes. We study the degree to which this approximation holds in the context of estimating the time to the most recent common ancestor (TMRCA) of a set of lineages. In an exponential growth scenario, we find that unless the product of population size (N) and growth rate (r) is at least ∼105, the “pairwise comparison estimator” of TMRCA that derives from the star genealogy assumption has bias of 10-50%. Thus, the estimator is appropriate only for large populations that have grown very rapidly. The “tree-length estimator” of TMRCA is more biased than the pairwise comparison estimator, having low bias only for extremely large values of Nr." @default.
• W1847444310 created "2016-06-24" @default.
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• W1847444310 date "2003-08-01" @default.
• W1847444310 modified "2023-09-24" @default.
• W1847444310 title "On the Use of Star-Shaped Genealogies in Inference of Coalescence Times" @default.
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• W1847444310 doi "https://doi.org/10.1093/genetics/164.4.1677" @default.
• W1847444310 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1462671" @default.
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