FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1848491851> ?p ?o ?g. }

• W1848491851 endingPage "390" @default.
• W1848491851 startingPage "385" @default.
• W1848491851 abstract "Asthma exacerbations are major contributors to asthma morbidity and rather difficult to treat. There is inconclusive evidence that macrolide antibiotics may have an effect on asthma exacerbations through their antibacterial and/or anti-inflammatory properties. The aim of the study was to evaluate the efficacy of clarithromycin on medium-term asthma activity when given as an add-on therapy in children with acute asthma.This pilot, open-labeled, randomized, prospective study included 40 school-aged children, with intermittent or mild persistent asthma, presenting with an acute exacerbation. Children were randomized to receive 15 mg/kg of clarithromycin for 3 wk, in addition to their regular (GINA-guided) exacerbation treatment. The microbial trigger of exacerbations was assessed by serology and PCR. Children were followed up with diary cards for 12 wk; lung function was assessed at entry, 3, and 12 wk after the exacerbation.Children in the clarithromycin group had significantly more symptom-free days (78 ± 2 vs. 69 ± 6 days, p < 0.00001) and less total number of periods with loss of control (9 vs. 19, respectively, p = 0.013) during the follow-up period, compared to controls. Moreover, treated children presented reduced duration of the index episode (5.0 ± 1 vs. 7.5 ± 1 days, p < 0.00001). Lung function did not differ between groups.When added to regular treatment, a 3-wk course of clarithromycin was associated with an increase in the number of symptom-free days, reductions in the number and severity of days with loss of control following index episode, and a decrease in the duration of the initial asthma exacerbation." @default.
• W1848491851 created "2016-06-24" @default.
• W1848491851 creator A5007014147 @default.
• W1848491851 creator A5041944228 @default.
• W1848491851 creator A5044065193 @default.
• W1848491851 creator A5056145906 @default.
• W1848491851 creator A5067318504 @default.
• W1848491851 creator A5082283190 @default.
• W1848491851 creator A5091178960 @default.
• W1848491851 date "2012-03-21" @default.
• W1848491851 modified "2023-09-26" @default.
• W1848491851 title "Effect of clarithromycin on acute asthma exacerbations in children: an open randomized study" @default.
• W1848491851 cites W1915722592 @default.
• W1848491851 cites W1964779747 @default.
• W1848491851 cites W1965011315 @default.
• W1848491851 cites W1974143308 @default.
• W1848491851 cites W1975184470 @default.
• W1848491851 cites W1976372716 @default.
• W1848491851 cites W1992110991 @default.
• W1848491851 cites W2004998422 @default.
• W1848491851 cites W2018086889 @default.
• W1848491851 cites W2030827695 @default.
• W1848491851 cites W2037466531 @default.
• W1848491851 cites W2058801648 @default.
• W1848491851 cites W2060021421 @default.
• W1848491851 cites W2062699124 @default.
• W1848491851 cites W2073277370 @default.
• W1848491851 cites W2111324648 @default.
• W1848491851 cites W2115548143 @default.
• W1848491851 cites W2118441693 @default.
• W1848491851 cites W2120613903 @default.
• W1848491851 cites W2133504637 @default.
• W1848491851 cites W2137125377 @default.
• W1848491851 cites W2142821022 @default.
• W1848491851 cites W2144888470 @default.
• W1848491851 cites W2155682059 @default.
• W1848491851 cites W2166363941 @default.
• W1848491851 cites W2168260020 @default.
• W1848491851 doi "https://doi.org/10.1111/j.1399-3038.2012.01280.x" @default.
• W1848491851 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22433020" @default.
• W1848491851 hasPublicationYear "2012" @default.
• W1848491851 type Work @default.
• W1848491851 sameAs 1848491851 @default.
• W1848491851 citedByCount "39" @default.
• W1848491851 countsByYear W18484918512012 @default.
• W1848491851 countsByYear W18484918512013 @default.
• W1848491851 countsByYear W18484918512014 @default.
• W1848491851 countsByYear W18484918512015 @default.
• W1848491851 countsByYear W18484918512016 @default.
• W1848491851 countsByYear W18484918512018 @default.
• W1848491851 countsByYear W18484918512019 @default.
• W1848491851 countsByYear W18484918512020 @default.
• W1848491851 countsByYear W18484918512021 @default.
• W1848491851 countsByYear W18484918512022 @default.
• W1848491851 crossrefType "journal-article" @default.
• W1848491851 hasAuthorship W1848491851A5007014147 @default.
• W1848491851 hasAuthorship W1848491851A5041944228 @default.
• W1848491851 hasAuthorship W1848491851A5044065193 @default.
• W1848491851 hasAuthorship W1848491851A5056145906 @default.
• W1848491851 hasAuthorship W1848491851A5067318504 @default.
• W1848491851 hasAuthorship W1848491851A5082283190 @default.
• W1848491851 hasAuthorship W1848491851A5091178960 @default.
• W1848491851 hasConcept C126322002 @default.
• W1848491851 hasConcept C168563851 @default.
• W1848491851 hasConcept C187212893 @default.
• W1848491851 hasConcept C2776042228 @default.
• W1848491851 hasConcept C2776409635 @default.
• W1848491851 hasConcept C2776962512 @default.
• W1848491851 hasConcept C2777014857 @default.
• W1848491851 hasConcept C2909082789 @default.
• W1848491851 hasConcept C501593827 @default.
• W1848491851 hasConcept C71924100 @default.
• W1848491851 hasConcept C86803240 @default.
• W1848491851 hasConcept C89423630 @default.
• W1848491851 hasConceptScore W1848491851C126322002 @default.
• W1848491851 hasConceptScore W1848491851C168563851 @default.
• W1848491851 hasConceptScore W1848491851C187212893 @default.
• W1848491851 hasConceptScore W1848491851C2776042228 @default.
• W1848491851 hasConceptScore W1848491851C2776409635 @default.
• W1848491851 hasConceptScore W1848491851C2776962512 @default.
• W1848491851 hasConceptScore W1848491851C2777014857 @default.
• W1848491851 hasConceptScore W1848491851C2909082789 @default.
• W1848491851 hasConceptScore W1848491851C501593827 @default.
• W1848491851 hasConceptScore W1848491851C71924100 @default.
• W1848491851 hasConceptScore W1848491851C86803240 @default.
• W1848491851 hasConceptScore W1848491851C89423630 @default.
• W1848491851 hasIssue "4" @default.
• W1848491851 hasLocation W18484918511 @default.
• W1848491851 hasLocation W18484918512 @default.
• W1848491851 hasOpenAccess W1848491851 @default.
• W1848491851 hasPrimaryLocation W18484918511 @default.
• W1848491851 hasRelatedWork W1957770986 @default.
• W1848491851 hasRelatedWork W1985426726 @default.
• W1848491851 hasRelatedWork W2375866322 @default.
• W1848491851 hasRelatedWork W2386381627 @default.
• W1848491851 hasRelatedWork W2886979045 @default.
• W1848491851 hasRelatedWork W2943761215 @default.
• W1848491851 hasRelatedWork W2962939929 @default.

• next