FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1848996936> ?p ?o ?g. }

• W1848996936 endingPage "740" @default.
• W1848996936 startingPage "729" @default.
• W1848996936 abstract "Abstract Coenzyme F 420 is a deazaflavin hydride carrier with a lower reduction potential than most flavins. In Mycobacterium tuberculosis ( Mtb ), F 420 plays an important role in activating PA‐824, an antituberculosis drug currently used in clinical trials. Although F 420 is important to Mtb redox metabolism, little is known about the enzymes that bind F 420 and the reactions that they catalyze. We have identified a novel F 420 ‐binding protein, Rv1155, which is annotated in the Mtb genome sequence as a putative flavin mononucleotide (FMN)‐binding protein. Using biophysical techniques, we have demonstrated that instead of binding FMN or other flavins, Rv1155 binds coenzyme F 420 . The crystal structure of the complex of Rv1155 and F 420 reveals one F 420 molecule bound to each monomer of the Rv1155 dimer. Structural, biophysical, and bioinformatic analyses of the Rv1155–F 420 complex provide clues about its role in the bacterium." @default.
• W1848996936 created "2016-06-24" @default.
• W1848996936 creator A5002890830 @default.
• W1848996936 creator A5002933612 @default.
• W1848996936 creator A5018322506 @default.
• W1848996936 creator A5039220931 @default.
• W1848996936 creator A5040311116 @default.
• W1848996936 creator A5056066848 @default.
• W1848996936 date "2015-03-10" @default.
• W1848996936 modified "2023-10-13" @default.
• W1848996936 title "Molecular insights into the binding of coenzyme <scp>F₄₂₀</scp> to the conserved protein <scp>R</scp>v1155 from <scp><i>M</i></scp><i>ycobacterium tuberculosis</i>" @default.
• W1848996936 cites W133044305 @default.
• W1848996936 cites W1538374398 @default.
• W1848996936 cites W1566278265 @default.
• W1848996936 cites W1904943041 @default.
• W1848996936 cites W1928840963 @default.
• W1848996936 cites W1973789730 @default.
• W1848996936 cites W1973867121 @default.
• W1848996936 cites W1981154770 @default.
• W1848996936 cites W1983208005 @default.
• W1848996936 cites W1986106712 @default.
• W1848996936 cites W1988361517 @default.
• W1848996936 cites W1991623807 @default.
• W1848996936 cites W1999268553 @default.
• W1848996936 cites W2000288572 @default.
• W1848996936 cites W2001769151 @default.
• W1848996936 cites W2009162081 @default.
• W1848996936 cites W2010320265 @default.
• W1848996936 cites W2011200526 @default.
• W1848996936 cites W2012869840 @default.
• W1848996936 cites W2017421343 @default.
• W1848996936 cites W2018385499 @default.
• W1848996936 cites W2022175846 @default.
• W1848996936 cites W2026766410 @default.
• W1848996936 cites W2027536884 @default.
• W1848996936 cites W2029433867 @default.
• W1848996936 cites W2030517878 @default.
• W1848996936 cites W2058167495 @default.
• W1848996936 cites W2063603291 @default.
• W1848996936 cites W2064407214 @default.
• W1848996936 cites W2067019748 @default.
• W1848996936 cites W2070424325 @default.
• W1848996936 cites W2077776336 @default.
• W1848996936 cites W2089429067 @default.
• W1848996936 cites W2094201044 @default.
• W1848996936 cites W2095307459 @default.
• W1848996936 cites W2104047596 @default.
• W1848996936 cites W2104827182 @default.
• W1848996936 cites W2105924489 @default.
• W1848996936 cites W2106391842 @default.
• W1848996936 cites W2110033896 @default.
• W1848996936 cites W2120574189 @default.
• W1848996936 cites W2121464522 @default.
• W1848996936 cites W2126918223 @default.
• W1848996936 cites W2132629607 @default.
• W1848996936 cites W2134094649 @default.
• W1848996936 cites W2140591070 @default.
• W1848996936 cites W2141885858 @default.
• W1848996936 cites W2152770371 @default.
• W1848996936 cites W2163271567 @default.
• W1848996936 cites W2167723995 @default.
• W1848996936 cites W2169645017 @default.
• W1848996936 cites W2180229411 @default.
• W1848996936 cites W4210400672 @default.
• W1848996936 cites W4252706339 @default.
• W1848996936 doi "https://doi.org/10.1002/pro.2645" @default.
• W1848996936 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4420522" @default.
• W1848996936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25644473" @default.
• W1848996936 hasPublicationYear "2015" @default.
• W1848996936 type Work @default.
• W1848996936 sameAs 1848996936 @default.
• W1848996936 citedByCount "16" @default.
• W1848996936 countsByYear W18489969362015 @default.
• W1848996936 countsByYear W18489969362016 @default.
• W1848996936 countsByYear W18489969362017 @default.
• W1848996936 countsByYear W18489969362018 @default.
• W1848996936 countsByYear W18489969362019 @default.
• W1848996936 countsByYear W18489969362020 @default.
• W1848996936 countsByYear W18489969362021 @default.
• W1848996936 crossrefType "journal-article" @default.
• W1848996936 hasAuthorship W1848996936A5002890830 @default.
• W1848996936 hasAuthorship W1848996936A5002933612 @default.
• W1848996936 hasAuthorship W1848996936A5018322506 @default.
• W1848996936 hasAuthorship W1848996936A5039220931 @default.
• W1848996936 hasAuthorship W1848996936A5040311116 @default.
• W1848996936 hasAuthorship W1848996936A5056066848 @default.
• W1848996936 hasBestOaLocation W18489969361 @default.
• W1848996936 hasConcept C107824862 @default.
• W1848996936 hasConcept C134651460 @default.
• W1848996936 hasConcept C142724271 @default.
• W1848996936 hasConcept C178790620 @default.
• W1848996936 hasConcept C181199279 @default.
• W1848996936 hasConcept C185592680 @default.
• W1848996936 hasConcept C197957613 @default.
• W1848996936 hasConcept C2777427158 @default.
• W1848996936 hasConcept C2777975735 @default.
• W1848996936 hasConcept C2779123261 @default.
• W1848996936 hasConcept C2779546866 @default.

• next