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- W1849242803 abstract "This review summarizes the important role of Anti-Müllerian hormone (Amh) during gonad development in fishes. This Tgfβ-domain bearing hormone was named after one of its known functions, the induction of the regression of Müllerian ducts in male mammalian embryos. Later in development it is involved in male and female gonad differentiation and extragonadal expression has been reported in mammals as well. Teleosts lack Müllerian ducts, but they have amh orthologous genes. amh expression is reported from 21 fish species and possible regulatory interactions with further factors like sex steroids and gonadotropic hormones are discussed. The gonadotropin Fsh inhibits amh expression in all fish species studied. Sex steroids show no consistent influence on amh expression. Amh is produced in male Sertoli cells and female granulosa cells and inhibits germ cell proliferation and differentiation as well as steroidogenesis in both sexes. Therefore, Amh might be a central player in gonad development and a target of gonadotropic Fsh. Furthermore, there is evidence that an Amh-type II receptor is involved in germ cell regulation. Amh and its corresponding type II receptor are also present in brain and pituitary, at least in some teleosts, indicating additional roles of Amh effects in the brain–pituitary–gonadal axis. Unraveling Amh signaling is important in stem cell research and for reproduction as well as for aquaculture and in environmental science." @default.
- W1849242803 created "2016-06-24" @default.
- W1849242803 creator A5029251413 @default.
- W1849242803 creator A5045304941 @default.
- W1849242803 creator A5068291702 @default.
- W1849242803 date "2015-11-01" @default.
- W1849242803 modified "2023-10-18" @default.
- W1849242803 title "The role of Amh signaling in teleost fish – Multiple functions not restricted to the gonads" @default.
- W1849242803 cites W1522803856 @default.
- W1849242803 cites W1528120845 @default.
- W1849242803 cites W1548475601 @default.
- W1849242803 cites W1554013411 @default.
- W1849242803 cites W1576518314 @default.
- W1849242803 cites W1871304706 @default.
- W1849242803 cites W1872697492 @default.
- W1849242803 cites W1910206150 @default.
- W1849242803 cites W1961534203 @default.
- W1849242803 cites W1963709884 @default.
- W1849242803 cites W1966559543 @default.
- W1849242803 cites W1968863496 @default.
- W1849242803 cites W1969565655 @default.
- W1849242803 cites W1969910626 @default.
- W1849242803 cites W1970263303 @default.
- W1849242803 cites W1972785483 @default.
- W1849242803 cites W1974368772 @default.
- W1849242803 cites W1974397196 @default.
- W1849242803 cites W1974886898 @default.
- W1849242803 cites W1978503814 @default.
- W1849242803 cites W1978752207 @default.
- W1849242803 cites W1979316890 @default.
- W1849242803 cites W1981338881 @default.
- W1849242803 cites W1981376235 @default.
- W1849242803 cites W1982052389 @default.
- W1849242803 cites W1982613306 @default.
- W1849242803 cites W1983476904 @default.
- W1849242803 cites W1983570177 @default.
- W1849242803 cites W1989894076 @default.
- W1849242803 cites W1990082168 @default.
- W1849242803 cites W1991604689 @default.
- W1849242803 cites W1992779707 @default.
- W1849242803 cites W1993692364 @default.
- W1849242803 cites W1995329979 @default.
- W1849242803 cites W1996358470 @default.
- W1849242803 cites W1996398586 @default.
- W1849242803 cites W1996621706 @default.
- W1849242803 cites W1996689072 @default.
- W1849242803 cites W1996875620 @default.
- W1849242803 cites W1999434762 @default.
- W1849242803 cites W2000440473 @default.
- W1849242803 cites W2001952613 @default.
- W1849242803 cites W2003035338 @default.
- W1849242803 cites W2003661581 @default.
- W1849242803 cites W2004370095 @default.
- W1849242803 cites W2006826132 @default.
- W1849242803 cites W2007969716 @default.
- W1849242803 cites W2010875404 @default.
- W1849242803 cites W2012174308 @default.
- W1849242803 cites W2012266374 @default.
- W1849242803 cites W2012380198 @default.
- W1849242803 cites W2012947487 @default.
- W1849242803 cites W2013246689 @default.
- W1849242803 cites W2015552576 @default.
- W1849242803 cites W2015750766 @default.
- W1849242803 cites W2017805515 @default.
- W1849242803 cites W2018475399 @default.
- W1849242803 cites W2019132245 @default.
- W1849242803 cites W2021748585 @default.
- W1849242803 cites W2022030472 @default.
- W1849242803 cites W2023804738 @default.
- W1849242803 cites W2026504016 @default.
- W1849242803 cites W2027573073 @default.
- W1849242803 cites W2029552542 @default.
- W1849242803 cites W2031271949 @default.
- W1849242803 cites W2031296143 @default.
- W1849242803 cites W2032101127 @default.
- W1849242803 cites W2032281322 @default.
- W1849242803 cites W2035083937 @default.
- W1849242803 cites W2035107915 @default.
- W1849242803 cites W2037395479 @default.
- W1849242803 cites W2039210383 @default.
- W1849242803 cites W2039404256 @default.
- W1849242803 cites W2039537273 @default.
- W1849242803 cites W2041608149 @default.
- W1849242803 cites W2041736756 @default.
- W1849242803 cites W2044932541 @default.
- W1849242803 cites W2045398119 @default.
- W1849242803 cites W2045519188 @default.
- W1849242803 cites W2047093681 @default.
- W1849242803 cites W2049147637 @default.
- W1849242803 cites W2051401308 @default.
- W1849242803 cites W2053175039 @default.
- W1849242803 cites W2054532151 @default.
- W1849242803 cites W2056034299 @default.
- W1849242803 cites W2056862681 @default.
- W1849242803 cites W2057013813 @default.
- W1849242803 cites W2057223558 @default.
- W1849242803 cites W2058965368 @default.
- W1849242803 cites W2058982399 @default.