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• W1849337921 startingPage "991" @default.
• W1849337921 abstract "Tandemly repeated 72-base-pair (bp) segments located between nucleotides 107 and 250 of the simian virus 40 genome are essential for early region transcription. The functional requirement for the 72-bp repeat was supplied even when that segment was translocated to several locations distant from, and in different orientation, relative to, the promoter. Regardless of the position of the 72-bp enhancer segment, transcription was initiated at the same locations as with the normal promoter. Translocation of the 72-bp repeat segment to other sites in the genome resulted in the appearance of DNase I hypersensitivity at that site in the intranuclear viral minichromosomes. One of the translocations which did not produce enhancement of early- and late-region expression also failed to create a DNase I-hypersensitive site at the translocated 72-bp segment." @default.
• W1849337921 created "2016-06-24" @default.
• W1849337921 creator A5032493751 @default.
• W1849337921 creator A5081013332 @default.
• W1849337921 date "1983-06-01" @default.
• W1849337921 modified "2023-10-04" @default.
• W1849337921 title "Simian virus 40 early- and late-region promoter functions are enhanced by the 72-base-pair repeat inserted at distant locations and inverted orientations." @default.
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• W1849337921 doi "https://doi.org/10.1128/mcb.3.6.991" @default.
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