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• W1849909466 abstract "The vitamin B-6 requirements of 12 men and women over 60 y old were studied. The protocol consisted of a 5-d baseline period and four experimental periods during which the subjects successively received 0.003, 0.015, 0.0225 and 0.03375 mg of vitamin B-6/(kg body wt·d). Dietary protein was 1.2 or 0.8 g/(kg body wt·d). At 5- or 6-d intervals, xanthurenic acid (XA) after a 5-g L-tryptophan load and 4-pyridoxic acid (4-PA) in 24-h urine, erythrocyte aspartate aminotransferase activity coefficient (EAST-AC) and plasma pyridoxal-5′-phosphate (PLP) were measured. These measurements were abnormal during vitamin B-6 depletion but returned to normal during repletion. Men who ingested ∼120 g protein/d required 1.96 ± 0.11 mg of vitamin B-6 to normalize XA; women who ingested 78 g protein/d required 1.90 ± 0.18 mg of vitamin B-6 to normalize XA. To attain normal levels of EAST-AC and 4-PA in men, 2.88 ± 0.17 mg of vitamin B-6 were needed; to normalize PLP, 1.96 ± 0.11 mg of vitamin.B-6 were required. Women required 1.90 ± 0.18 mg or more of vitamin B-6 to normalize these measurements. Vitamin B-6 requirements were not decreased in two of three subjects who ingested 54 g of protein daily. Thus, vitamin B-6 requirements of elderly men and women are about 1.96 and 1.90 mg/d, respectively." @default.
• W1849909466 created "2016-06-24" @default.
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• W1849909466 date "1991-07-01" @default.
• W1849909466 modified "2023-10-03" @default.
• W1849909466 title "Vitamin B-6 Requirements of Elderly Men and Women" @default.
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• W1849909466 doi "https://doi.org/10.1093/jn/121.7.1062" @default.
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