FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1850331043> ?p ?o ?g. }

• W1850331043 endingPage "675" @default.
• W1850331043 startingPage "668" @default.
• W1850331043 abstract "Although cisplatin-based chemotherapy is considered to be the treatment of choice for metastatic bladder cancer, its efficacy and tolerability has proven to be limited. MicroRNAs are small noncoding RNAs, whose genes are frequently organized in clusters. These molecules constitute posttranscriptional regulators of mRNA expression and are claimed to be deregulated in cancer. miR-143/145 and miR-183/96/182 clusters have been extensively studied in bladder cancer cells. Herein, we tried to add up to this knowledge by assessing the expression levels of the five mature microRNAs derived from the aforementioned clusters in T24 bladder cancer cells exposed to either cisplatin or paclitaxel. For both compounds, the viability of treated T24 cells was estimated via the MTT colorimetric assay and the Trypan Blue exclusion method, while a fraction of the cells was left to recover. The expression levels of all mature microRNAs were finally quantified both in treated and in recovered cells by performing real-time PCR. According to our data, cisplatin and paclitaxel strongly decreased T24 cells' viability, showing in parallel the ability to significantly down-regulate miR-143 levels, and up-regulate the expression levels of miR-145, miR-183, miR-96, and miR-182, which, in their total, demonstrated case-specific variations after recovery period." @default.
• W1850331043 created "2016-06-24" @default.
• W1850331043 creator A5022608205 @default.
• W1850331043 creator A5085601430 @default.
• W1850331043 date "2015-09-10" @default.
• W1850331043 modified "2023-09-25" @default.
• W1850331043 title "Cisplatin and Paclitaxel Alter the Expression Pattern of miR-143/145 and miR-183/96/182 Clusters in T24 Bladder Cancer Cells" @default.
• W1850331043 cites W1524739268 @default.
• W1850331043 cites W1578339880 @default.
• W1850331043 cites W169084277 @default.
• W1850331043 cites W1847493486 @default.
• W1850331043 cites W1869904952 @default.
• W1850331043 cites W1974254202 @default.
• W1850331043 cites W1980462191 @default.
• W1850331043 cites W1981126547 @default.
• W1850331043 cites W1987604182 @default.
• W1850331043 cites W1997683783 @default.
• W1850331043 cites W2000148814 @default.
• W1850331043 cites W2006247279 @default.
• W1850331043 cites W2014571376 @default.
• W1850331043 cites W2016534280 @default.
• W1850331043 cites W2019156893 @default.
• W1850331043 cites W2030900217 @default.
• W1850331043 cites W2033311505 @default.
• W1850331043 cites W2037090973 @default.
• W1850331043 cites W2046237288 @default.
• W1850331043 cites W2053555736 @default.
• W1850331043 cites W2055744006 @default.
• W1850331043 cites W2057123716 @default.
• W1850331043 cites W2057690836 @default.
• W1850331043 cites W2067053182 @default.
• W1850331043 cites W2073118251 @default.
• W1850331043 cites W2075419238 @default.
• W1850331043 cites W2076439746 @default.
• W1850331043 cites W2080922093 @default.
• W1850331043 cites W2103005678 @default.
• W1850331043 cites W2107277218 @default.
• W1850331043 cites W2113539023 @default.
• W1850331043 cites W2114557056 @default.
• W1850331043 cites W2130517519 @default.
• W1850331043 cites W2132054434 @default.
• W1850331043 cites W2162130153 @default.
• W1850331043 cites W2163245419 @default.
• W1850331043 cites W2168138060 @default.
• W1850331043 cites W2170552969 @default.
• W1850331043 cites W2170618275 @default.
• W1850331043 cites W2192080449 @default.
• W1850331043 cites W2323860656 @default.
• W1850331043 cites W4313635027 @default.
• W1850331043 doi "https://doi.org/10.1111/cts.12323" @default.
• W1850331043 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5351132" @default.
• W1850331043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26356996" @default.
• W1850331043 hasPublicationYear "2015" @default.
• W1850331043 type Work @default.
• W1850331043 sameAs 1850331043 @default.
• W1850331043 citedByCount "10" @default.
• W1850331043 countsByYear W18503310432016 @default.
• W1850331043 countsByYear W18503310432017 @default.
• W1850331043 countsByYear W18503310432018 @default.
• W1850331043 countsByYear W18503310432019 @default.
• W1850331043 countsByYear W18503310432020 @default.
• W1850331043 countsByYear W18503310432021 @default.
• W1850331043 countsByYear W18503310432022 @default.
• W1850331043 crossrefType "journal-article" @default.
• W1850331043 hasAuthorship W1850331043A5022608205 @default.
• W1850331043 hasAuthorship W1850331043A5085601430 @default.
• W1850331043 hasBestOaLocation W18503310432 @default.
• W1850331043 hasConcept C104317684 @default.
• W1850331043 hasConcept C121608353 @default.
• W1850331043 hasConcept C145059251 @default.
• W1850331043 hasConcept C1491633281 @default.
• W1850331043 hasConcept C153911025 @default.
• W1850331043 hasConcept C197934379 @default.
• W1850331043 hasConcept C2776694085 @default.
• W1850331043 hasConcept C2777292972 @default.
• W1850331043 hasConcept C2778239845 @default.
• W1850331043 hasConcept C2778375690 @default.
• W1850331043 hasConcept C2780070996 @default.
• W1850331043 hasConcept C2780352672 @default.
• W1850331043 hasConcept C2780783641 @default.
• W1850331043 hasConcept C502942594 @default.
• W1850331043 hasConcept C53227056 @default.
• W1850331043 hasConcept C54355233 @default.
• W1850331043 hasConcept C55493867 @default.
• W1850331043 hasConcept C71924100 @default.
• W1850331043 hasConcept C86803240 @default.
• W1850331043 hasConcept C96232424 @default.
• W1850331043 hasConcept C98274493 @default.
• W1850331043 hasConceptScore W1850331043C104317684 @default.
• W1850331043 hasConceptScore W1850331043C121608353 @default.
• W1850331043 hasConceptScore W1850331043C145059251 @default.
• W1850331043 hasConceptScore W1850331043C1491633281 @default.
• W1850331043 hasConceptScore W1850331043C153911025 @default.
• W1850331043 hasConceptScore W1850331043C197934379 @default.
• W1850331043 hasConceptScore W1850331043C2776694085 @default.
• W1850331043 hasConceptScore W1850331043C2777292972 @default.
• W1850331043 hasConceptScore W1850331043C2778239845 @default.
• W1850331043 hasConceptScore W1850331043C2778375690 @default.

• next