FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1850537255> ?p ?o ?g. }

• W1850537255 endingPage "495" @default.
• W1850537255 startingPage "490" @default.
• W1850537255 abstract "While all patients with cystic fibrosis (CF) have mutations in both CFTR alleles, often only one CFTR change is detected in patients with other lung disorders. The aim of this study was to investigate whether heterozygosity for CFTR mutations could be a determinant risk factor in the development of bronchiectasis in adult patients. We have performed the CFTR gene analysis in a cohort of 55 bronchiectasis adult patients with unknown etiology. The 5T variant (TG)m and the M470V polymorphisms were also analyzed. A general population in which the same molecular analysis was previously performed was used as the control group. The mutational spectrum of patients was also compared with that found in our CF population. CFTR mutations/variants were found in 20 patients (36%), 14 with only one mutant gene (25%). All six patients colonized by Staphylococcus aureus presented with at least one CFTR change (p = 0.001). No statistical significance was observed between patients with and without mutations for other clinical features. The 5T variant was found in four patients. Additionally, 90% of patients with mutations had the more functional M470 allele (p < 0.001). These results suggest the involvement of the CFTR gene in bronchiectasis of unknown etiology in adult patients." @default.
• W1850537255 created "2016-06-24" @default.
• W1850537255 creator A5000885820 @default.
• W1850537255 creator A5014662878 @default.
• W1850537255 creator A5023076740 @default.
• W1850537255 creator A5025684131 @default.
• W1850537255 creator A5027981398 @default.
• W1850537255 creator A5031153935 @default.
• W1850537255 creator A5045451488 @default.
• W1850537255 creator A5064188458 @default.
• W1850537255 creator A5066870459 @default.
• W1850537255 creator A5085943110 @default.
• W1850537255 date "2004-05-18" @default.
• W1850537255 modified "2023-10-15" @default.
• W1850537255 title "Bronchiectasis in adult patients: an expression of heterozygosity for <i>CFTR</i> gene mutations?" @default.
• W1850537255 cites W1946951765 @default.
• W1850537255 cites W1976858537 @default.
• W1850537255 cites W1997994303 @default.
• W1850537255 cites W2007006471 @default.
• W1850537255 cites W2013912459 @default.
• W1850537255 cites W2016013412 @default.
• W1850537255 cites W2019585154 @default.
• W1850537255 cites W2023243075 @default.
• W1850537255 cites W2029299728 @default.
• W1850537255 cites W2036606154 @default.
• W1850537255 cites W2039720197 @default.
• W1850537255 cites W2076534479 @default.
• W1850537255 cites W2096867732 @default.
• W1850537255 cites W2105292130 @default.
• W1850537255 cites W2117559755 @default.
• W1850537255 cites W2119219430 @default.
• W1850537255 cites W2125391335 @default.
• W1850537255 cites W2126609769 @default.
• W1850537255 cites W2139574634 @default.
• W1850537255 cites W2145784700 @default.
• W1850537255 cites W2154467209 @default.
• W1850537255 cites W2167477001 @default.
• W1850537255 cites W4240997916 @default.
• W1850537255 doi "https://doi.org/10.1111/j.0009-9163.2004.00265.x" @default.
• W1850537255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15151509" @default.
• W1850537255 hasPublicationYear "2004" @default.
• W1850537255 type Work @default.
• W1850537255 sameAs 1850537255 @default.
• W1850537255 citedByCount "80" @default.
• W1850537255 countsByYear W18505372552012 @default.
• W1850537255 countsByYear W18505372552013 @default.
• W1850537255 countsByYear W18505372552015 @default.
• W1850537255 countsByYear W18505372552016 @default.
• W1850537255 countsByYear W18505372552017 @default.
• W1850537255 countsByYear W18505372552018 @default.
• W1850537255 countsByYear W18505372552019 @default.
• W1850537255 countsByYear W18505372552020 @default.
• W1850537255 countsByYear W18505372552021 @default.
• W1850537255 countsByYear W18505372552022 @default.
• W1850537255 countsByYear W18505372552023 @default.
• W1850537255 crossrefType "journal-article" @default.
• W1850537255 hasAuthorship W1850537255A5000885820 @default.
• W1850537255 hasAuthorship W1850537255A5014662878 @default.
• W1850537255 hasAuthorship W1850537255A5023076740 @default.
• W1850537255 hasAuthorship W1850537255A5025684131 @default.
• W1850537255 hasAuthorship W1850537255A5027981398 @default.
• W1850537255 hasAuthorship W1850537255A5031153935 @default.
• W1850537255 hasAuthorship W1850537255A5045451488 @default.
• W1850537255 hasAuthorship W1850537255A5064188458 @default.
• W1850537255 hasAuthorship W1850537255A5066870459 @default.
• W1850537255 hasAuthorship W1850537255A5085943110 @default.
• W1850537255 hasConcept C104317684 @default.
• W1850537255 hasConcept C126322002 @default.
• W1850537255 hasConcept C137627325 @default.
• W1850537255 hasConcept C143589142 @default.
• W1850537255 hasConcept C180754005 @default.
• W1850537255 hasConcept C2776938444 @default.
• W1850537255 hasConcept C2777714996 @default.
• W1850537255 hasConcept C2779379686 @default.
• W1850537255 hasConcept C2908647359 @default.
• W1850537255 hasConcept C501734568 @default.
• W1850537255 hasConcept C54355233 @default.
• W1850537255 hasConcept C71924100 @default.
• W1850537255 hasConcept C86803240 @default.
• W1850537255 hasConcept C90924648 @default.
• W1850537255 hasConcept C99454951 @default.
• W1850537255 hasConceptScore W1850537255C104317684 @default.
• W1850537255 hasConceptScore W1850537255C126322002 @default.
• W1850537255 hasConceptScore W1850537255C137627325 @default.
• W1850537255 hasConceptScore W1850537255C143589142 @default.
• W1850537255 hasConceptScore W1850537255C180754005 @default.
• W1850537255 hasConceptScore W1850537255C2776938444 @default.
• W1850537255 hasConceptScore W1850537255C2777714996 @default.
• W1850537255 hasConceptScore W1850537255C2779379686 @default.
• W1850537255 hasConceptScore W1850537255C2908647359 @default.
• W1850537255 hasConceptScore W1850537255C501734568 @default.
• W1850537255 hasConceptScore W1850537255C54355233 @default.
• W1850537255 hasConceptScore W1850537255C71924100 @default.
• W1850537255 hasConceptScore W1850537255C86803240 @default.
• W1850537255 hasConceptScore W1850537255C90924648 @default.
• W1850537255 hasConceptScore W1850537255C99454951 @default.
• W1850537255 hasIssue "6" @default.
• W1850537255 hasLocation W18505372551 @default.

• next