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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1850872537> ?p ?o ?g. }

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• W1850872537 abstract "Single-stranded fragments of adenovirus type 2 DNA were isolated from infected KB cells under conditions which retarded reassociation of complementary sequences but did not denature native viral DNA. Of the total intracellular, virus-specific DNA labeled during a 1-h pulse with tritiated thymidine begining 15 h after infection, about 20% was single stranded when fractionated on hydroxylapatite. This DNA shifted predominantly to the double-stranded fraction on hydroxylapatite during an extended chase incubation, suggesting that it may represent single-stranded DNA in replicating intermediates. Furthermore, the single-stranded DNA annealed nearly equally to both strands of the adenovirus genome. These findings indicate that at least portions of both complementary strands of adenovirus type 2 DNA are exposed as single strands during the period of viral DNA synthesis." @default.
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• W1850872537 date "1975-10-01" @default.
• W1850872537 modified "2023-09-25" @default.
• W1850872537 title "Isolation and partial characterization of single-stranded adenoviral DNA produced during synthesis of adenovirus type 2 DNA" @default.
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• W1850872537 doi "https://doi.org/10.1128/jvi.16.4.775-782.1975" @default.
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