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- W185193360 abstract "Copper complexes of several naturally occurring L-amino acids and D-Pencillamine were synthesized. These compounds were evaluated for their antiulcer, activities in the Shay model of rat ulcer. All complexes were found to be effective in reducing the severity and/or number of ulcers as well as In reducing Shay rat mortality. Antiulcer activity of copper-amino acid complexes. was Found to decrease with increasing lipophilicity of the ligand. All copper-complexes containing L-histidine as a ligand were found to be poorly active. Formation of copper-histamine complex in vivo is suggested as a possible mechanism of action of these compounds." @default.
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- W185193360 date "1982-01-01" @default.
- W185193360 modified "2023-09-24" @default.
- W185193360 title "The Antiulcer Activities of Copper Complexes" @default.
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- W185193360 doi "https://doi.org/10.1007/978-1-4612-5829-2_34" @default.
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