FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1852183102> ?p ?o ?g. }

• W1852183102 endingPage "260" @default.
• W1852183102 startingPage "249" @default.
• W1852183102 abstract "Bipolar disorder may be characterized by a hypersensitivity to reward-relevant stimuli, potentially underlying the emotional lability and dysregulation that characterizes the illness. In parallel, research highlights the predominant role of striatal and orbitofrontal cortical (OFC) regions in reward-processing and approach-related affect. We aimed to examine whether bipolar disorder, relative to healthy, participants displayed elevated activity in these regions during reward processing.Twenty-one euthymic bipolar I disorder and 20 healthy control participants with no lifetime history of psychiatric disorder underwent functional magnetic resonance imaging (fMRI) scanning during a card-guessing paradigm designed to examine reward-related brain function to anticipation and receipt of monetary reward and loss. Data were collected using a 3T Siemens Trio scanner.Region-of-interest analyses revealed that bipolar disorder participants displayed greater ventral striatal and right-sided orbitofrontal [Brodmann area (BA) 11] activity during anticipation, but not outcome, of monetary reward relative to healthy controls (p < 0.05, corrected). Whole-brain analyses indicated that bipolar disorder, relative to healthy, participants also displayed elevated left-lateral OFC (BA 47) activity during reward anticipation (p < 0.05, corrected).Elevated ventral striatal and OFC activity during reward anticipation may represent a neural mechanism for predisposition to expansive mood and hypo/mania in response to reward-relevant cues that characterizes bipolar disorder. Our findings contrast with research reporting blunted activity in the ventral striatum during reward processing in unipolar depressed individuals, relative to healthy controls. Examination of reward-related neural activity in bipolar disorder is a promising research focus to facilitate identification of biological markers of the illness." @default.
• W1852183102 created "2016-06-24" @default.
• W1852183102 creator A5007325929 @default.
• W1852183102 creator A5017804271 @default.
• W1852183102 creator A5049941307 @default.
• W1852183102 creator A5054013085 @default.
• W1852183102 creator A5058207550 @default.
• W1852183102 creator A5061001915 @default.
• W1852183102 creator A5078924853 @default.
• W1852183102 creator A5085276086 @default.
• W1852183102 date "2012-05-01" @default.
• W1852183102 modified "2023-10-14" @default.
• W1852183102 title "Waiting to win: elevated striatal and orbitofrontal cortical activity during reward anticipation in euthymic bipolar disorder adults" @default.
• W1852183102 cites W1510896541 @default.
• W1852183102 cites W1555129409 @default.
• W1852183102 cites W1847168837 @default.
• W1852183102 cites W1952680005 @default.
• W1852183102 cites W1970090972 @default.
• W1852183102 cites W1976113841 @default.
• W1852183102 cites W1979636244 @default.
• W1852183102 cites W1990144469 @default.
• W1852183102 cites W1996316196 @default.
• W1852183102 cites W1996449347 @default.
• W1852183102 cites W1999689183 @default.
• W1852183102 cites W2010891863 @default.
• W1852183102 cites W2035633002 @default.
• W1852183102 cites W2038068277 @default.
• W1852183102 cites W2045088017 @default.
• W1852183102 cites W2059057223 @default.
• W1852183102 cites W2080350725 @default.
• W1852183102 cites W2080839667 @default.
• W1852183102 cites W2086260698 @default.
• W1852183102 cites W2099080722 @default.
• W1852183102 cites W2100036649 @default.
• W1852183102 cites W2100087641 @default.
• W1852183102 cites W2106261260 @default.
• W1852183102 cites W2109662877 @default.
• W1852183102 cites W2111464173 @default.
• W1852183102 cites W2119285123 @default.
• W1852183102 cites W2126372302 @default.
• W1852183102 cites W2128472904 @default.
• W1852183102 cites W2134128653 @default.
• W1852183102 cites W2138309161 @default.
• W1852183102 cites W2151002558 @default.
• W1852183102 cites W2152923768 @default.
• W1852183102 cites W2166735517 @default.
• W1852183102 cites W4253478725 @default.
• W1852183102 cites W4254029742 @default.
• W1852183102 cites W4294307687 @default.
• W1852183102 cites W4296396329 @default.
• W1852183102 doi "https://doi.org/10.1111/j.1399-5618.2012.01012.x" @default.
• W1852183102 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3826255" @default.
• W1852183102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22548898" @default.
• W1852183102 hasPublicationYear "2012" @default.
• W1852183102 type Work @default.
• W1852183102 sameAs 1852183102 @default.
• W1852183102 citedByCount "213" @default.
• W1852183102 countsByYear W18521831022012 @default.
• W1852183102 countsByYear W18521831022013 @default.
• W1852183102 countsByYear W18521831022014 @default.
• W1852183102 countsByYear W18521831022015 @default.
• W1852183102 countsByYear W18521831022016 @default.
• W1852183102 countsByYear W18521831022017 @default.
• W1852183102 countsByYear W18521831022018 @default.
• W1852183102 countsByYear W18521831022019 @default.
• W1852183102 countsByYear W18521831022020 @default.
• W1852183102 countsByYear W18521831022021 @default.
• W1852183102 countsByYear W18521831022022 @default.
• W1852183102 countsByYear W18521831022023 @default.
• W1852183102 crossrefType "journal-article" @default.
• W1852183102 hasAuthorship W1852183102A5007325929 @default.
• W1852183102 hasAuthorship W1852183102A5017804271 @default.
• W1852183102 hasAuthorship W1852183102A5049941307 @default.
• W1852183102 hasAuthorship W1852183102A5054013085 @default.
• W1852183102 hasAuthorship W1852183102A5058207550 @default.
• W1852183102 hasAuthorship W1852183102A5061001915 @default.
• W1852183102 hasAuthorship W1852183102A5078924853 @default.
• W1852183102 hasAuthorship W1852183102A5085276086 @default.
• W1852183102 hasBestOaLocation W18521831022 @default.
• W1852183102 hasConcept C143661069 @default.
• W1852183102 hasConcept C154945302 @default.
• W1852183102 hasConcept C15744967 @default.
• W1852183102 hasConcept C169760540 @default.
• W1852183102 hasConcept C169900460 @default.
• W1852183102 hasConcept C176777502 @default.
• W1852183102 hasConcept C2776174506 @default.
• W1852183102 hasConcept C2776552330 @default.
• W1852183102 hasConcept C2776559556 @default.
• W1852183102 hasConcept C2776743251 @default.
• W1852183102 hasConcept C2776809841 @default.
• W1852183102 hasConcept C2778609679 @default.
• W1852183102 hasConcept C2779226451 @default.
• W1852183102 hasConcept C2780062018 @default.
• W1852183102 hasConcept C2780733359 @default.
• W1852183102 hasConcept C2781195155 @default.
• W1852183102 hasConcept C41008148 @default.
• W1852183102 hasConcept C513476851 @default.
• W1852183102 hasConcept C64948172 @default.

• next