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- W1852359153 abstract "Plants produce a wide diversity of secondary metabolites (SM) which serve them as defense compounds against herbivores, and other plants and microbes, but also as signal compounds. In general, SM exhibit a wide array of biological and pharmacological properties. Because of this, some plants or products isolated from them have been and are still used to treat infections, health disorders or diseases. This review provides evidence that many SM have a broad spectrum of bioactivities. They often interact with the main targets in cells, such as proteins, biomembranes or nucleic acids. Whereas some SM appear to have been optimized on a few molecular targets, such as alkaloids on receptors of neurotransmitters, others (such as phenolics and terpenoids) are less specific and attack a multitude of proteins by building hydrogen, hydrophobic and ionic bonds, thus modulating their 3D structures and in consequence their bioactivities. The main modes of action are described for the major groups of common plant secondary metabolites. The multitarget activities of many SM can explain the medical application of complex extracts from medicinal plants for more health disorders which involve several targets. Herbal medicine is not a placebo medicine but a rational medicine, and for several of them clinical trials have shown efficacy." @default.
- W1852359153 created "2016-06-24" @default.
- W1852359153 creator A5085626185 @default.
- W1852359153 date "2015-09-08" @default.
- W1852359153 modified "2023-10-16" @default.
- W1852359153 title "Modes of Action of Herbal Medicines and Plant Secondary Metabolites" @default.
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- W1852359153 cites W1481361569 @default.
- W1852359153 cites W1545076822 @default.
- W1852359153 cites W1600437736 @default.
- W1852359153 cites W1757820249 @default.
- W1852359153 cites W1966303307 @default.
- W1852359153 cites W1969042389 @default.
- W1852359153 cites W1969054982 @default.
- W1852359153 cites W1975831195 @default.
- W1852359153 cites W1976907017 @default.
- W1852359153 cites W1979099628 @default.
- W1852359153 cites W1980234364 @default.
- W1852359153 cites W1982488247 @default.
- W1852359153 cites W1987940883 @default.
- W1852359153 cites W1989674313 @default.
- W1852359153 cites W1993598475 @default.
- W1852359153 cites W1995580663 @default.
- W1852359153 cites W1998941123 @default.
- W1852359153 cites W2000805930 @default.
- W1852359153 cites W2002086112 @default.
- W1852359153 cites W2003210771 @default.
- W1852359153 cites W2008568206 @default.
- W1852359153 cites W2009617720 @default.
- W1852359153 cites W2010906156 @default.
- W1852359153 cites W2011032714 @default.
- W1852359153 cites W2015269523 @default.
- W1852359153 cites W2020062815 @default.
- W1852359153 cites W2021151992 @default.
- W1852359153 cites W2027856066 @default.
- W1852359153 cites W2029584430 @default.
- W1852359153 cites W2035321443 @default.
- W1852359153 cites W2036113298 @default.
- W1852359153 cites W2038698147 @default.
- W1852359153 cites W2039819146 @default.
- W1852359153 cites W2041874267 @default.
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- W1852359153 cites W2076195091 @default.
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- W1852359153 cites W2081941399 @default.
- W1852359153 cites W2091876048 @default.
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- W1852359153 cites W2128380808 @default.
- W1852359153 cites W2136183259 @default.
- W1852359153 cites W2159400527 @default.
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- W1852359153 doi "https://doi.org/10.3390/medicines2030251" @default.
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