FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1852646540> ?p ?o ?g. }

• W1852646540 endingPage "3969" @default.
• W1852646540 startingPage "3952" @default.
• W1852646540 abstract "Glycine is the major inhibitory neurotransmitter in the spinal cord and brainstem and is also required for the activation of NMDA receptors. The extracellular concentration of this neuroactive amino acid is regulated by at least two glycine transporters (GLYT1 and GLYT2). To study the localization and properties of these proteins, sequence-specific antibodies against the cloned glycine transporters have been raised. Immunoblots show that the 50-70 kDa band corresponding to GLYT1 is expressed at the highest concentrations in the spinal cord, brainstem, diencephalon, and retina, and, in a lesser degree, to the olfactory bulb and brain hemispheres, whereas it is not detected in peripheral tissues. Pre-embedding light and electron microscopic immunocytochemistry show that GLYT1 is expressed in glial cells around both glycinergic and nonglycinergic neurons except in the retina, where it is expressed by amacrine neurons, but not by glia. The expression of a 90-110 kDa band corresponding to GLYT2 is restricted to the spinal cord, brain-stem, and cerebellum; in addition, very low levels occur in the diencephalon. GLYT2 is found in presynaptic elements of neurons thought to be glycinergic. However, in the cerebellum, GLYT2 is expressed both in terminal boutons and in glial elements. The physiological consequences of the regional and cellular distributions of these two proteins as well as the possibility of the existence of an unidentified neuronal form of GLYT1 are discussed." @default.
• W1852646540 created "2016-06-24" @default.
• W1852646540 creator A5011796169 @default.
• W1852646540 creator A5014166421 @default.
• W1852646540 creator A5031611004 @default.
• W1852646540 creator A5055592485 @default.
• W1852646540 creator A5056517118 @default.
• W1852646540 creator A5071129392 @default.
• W1852646540 date "1995-05-01" @default.
• W1852646540 modified "2023-09-25" @default.
• W1852646540 title "Glycine transporters are differentially expressed among CNS cells" @default.
• W1852646540 cites W141762605 @default.
• W1852646540 cites W1509513803 @default.
• W1852646540 cites W1517440098 @default.
• W1852646540 cites W1554460251 @default.
• W1852646540 cites W1559268142 @default.
• W1852646540 cites W1578249395 @default.
• W1852646540 cites W1582272079 @default.
• W1852646540 cites W1775749144 @default.
• W1852646540 cites W1848756280 @default.
• W1852646540 cites W1870793636 @default.
• W1852646540 cites W1934020811 @default.
• W1852646540 cites W1940843357 @default.
• W1852646540 cites W1964094660 @default.
• W1852646540 cites W1964101344 @default.
• W1852646540 cites W1966682237 @default.
• W1852646540 cites W1976297771 @default.
• W1852646540 cites W1980253852 @default.
• W1852646540 cites W1980263219 @default.
• W1852646540 cites W1981604210 @default.
• W1852646540 cites W1983197885 @default.
• W1852646540 cites W1990166061 @default.
• W1852646540 cites W1991442236 @default.
• W1852646540 cites W1991701465 @default.
• W1852646540 cites W1991818630 @default.
• W1852646540 cites W1992313853 @default.
• W1852646540 cites W1998478437 @default.
• W1852646540 cites W2001121868 @default.
• W1852646540 cites W2003266390 @default.
• W1852646540 cites W2022200746 @default.
• W1852646540 cites W2026971413 @default.
• W1852646540 cites W2027905503 @default.
• W1852646540 cites W2028836570 @default.
• W1852646540 cites W2034845337 @default.
• W1852646540 cites W2042887832 @default.
• W1852646540 cites W2043057314 @default.
• W1852646540 cites W2046358120 @default.
• W1852646540 cites W2048587579 @default.
• W1852646540 cites W2051895501 @default.
• W1852646540 cites W2051918534 @default.
• W1852646540 cites W2056960549 @default.
• W1852646540 cites W2060118024 @default.
• W1852646540 cites W2071780344 @default.
• W1852646540 cites W2073003982 @default.
• W1852646540 cites W2074361827 @default.
• W1852646540 cites W2077346216 @default.
• W1852646540 cites W2079507733 @default.
• W1852646540 cites W2081678712 @default.
• W1852646540 cites W2083674889 @default.
• W1852646540 cites W2089244845 @default.
• W1852646540 cites W2124990645 @default.
• W1852646540 cites W2131384556 @default.
• W1852646540 cites W2145533695 @default.
• W1852646540 cites W2163815564 @default.
• W1852646540 cites W2206143948 @default.
• W1852646540 cites W2342328537 @default.
• W1852646540 cites W2417340247 @default.
• W1852646540 cites W2986312945 @default.
• W1852646540 doi "https://doi.org/10.1523/jneurosci.15-05-03952.1995" @default.
• W1852646540 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6578198" @default.
• W1852646540 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7751957" @default.
• W1852646540 hasPublicationYear "1995" @default.
• W1852646540 type Work @default.
• W1852646540 sameAs 1852646540 @default.
• W1852646540 citedByCount "483" @default.
• W1852646540 countsByYear W18526465402012 @default.
• W1852646540 countsByYear W18526465402013 @default.
• W1852646540 countsByYear W18526465402014 @default.
• W1852646540 countsByYear W18526465402015 @default.
• W1852646540 countsByYear W18526465402016 @default.
• W1852646540 countsByYear W18526465402017 @default.
• W1852646540 countsByYear W18526465402018 @default.
• W1852646540 countsByYear W18526465402019 @default.
• W1852646540 countsByYear W18526465402020 @default.
• W1852646540 countsByYear W18526465402021 @default.
• W1852646540 countsByYear W18526465402022 @default.
• W1852646540 countsByYear W18526465402023 @default.
• W1852646540 crossrefType "journal-article" @default.
• W1852646540 hasAuthorship W1852646540A5011796169 @default.
• W1852646540 hasAuthorship W1852646540A5014166421 @default.
• W1852646540 hasAuthorship W1852646540A5031611004 @default.
• W1852646540 hasAuthorship W1852646540A5055592485 @default.
• W1852646540 hasAuthorship W1852646540A5056517118 @default.
• W1852646540 hasAuthorship W1852646540A5071129392 @default.
• W1852646540 hasBestOaLocation W18526465401 @default.
• W1852646540 hasConcept C134018914 @default.
• W1852646540 hasConcept C169760540 @default.
• W1852646540 hasConcept C201750760 @default.

• next