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• W185280793 endingPage "70" @default.
• W185280793 startingPage "47" @default.
• W185280793 abstract "About 40 years ago it was recognized that a humoral factor, later identified as erythropoietin (Epo), was able to regulate the response of bone marrow to changes in red cell mass.1,2 It was also found that Epo was produced by the kidney in response to renal tissue hypoxia,3,4 and a quantitative assay based on the measurement of newly produced red cells labeled with59Fe was developed.2,5 The introduction of assays that allow cells to proliferate and differentiate in culture has led to the conclusion that Epo primarily acts on cells morphologically unrecognizable as erytroblasts. Semisolid cultures using methylcellulose, plasma-clot, and agar6–9 showed that two classes of erythroid progenitors can be observed at different times of incubation.7,8,10 Human bone marrow mononuclear cells in culture give rise to erythroid colonies after 4 to 5 days of incubation,11 while a longer (8–9 days) incubation time determines the appearance of larger colonies,7 and even larger and more hemoglobinized ones appear after 14 days. The first type is currently defined as colony-forming unit-erythroid (CFU-E)8; 14 and 8- to 9-day colonies are referred to as burst-forming unit-erythroid (BFU-E)12 and intermediate BFU-E,7 respectively (Fig. 3.1). Murine counterparts of these cells grow after 2 (CFU-E), 3 to 4 (intermediate BFU-E), and 8 (BFU-E) days.13 In addition, a murine progenitor with higher proliferative and differentiative capacity is seen after 9 to 12 days of incubation.7 KeywordsRecombinant Human ErythropoietinErythroid ProgenitorHumoral RegulationErythroid ColoniErythroid Colony FormationThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
• W185280793 created "2016-06-24" @default.
• W185280793 creator A5046772202 @default.
• W185280793 creator A5054336348 @default.
• W185280793 creator A5068835269 @default.
• W185280793 creator A5081187786 @default.
• W185280793 date "1993-01-01" @default.
• W185280793 modified "2023-09-26" @default.
• W185280793 title "The Humoral Regulation of Normal and Pathologic Erythropoiesis" @default.
• W185280793 cites W108654399 @default.
• W185280793 cites W1504261494 @default.
• W185280793 cites W150993113 @default.
• W185280793 cites W152767088 @default.
• W185280793 cites W1528664908 @default.
• W185280793 cites W1531716687 @default.
• W185280793 cites W1546467075 @default.
• W185280793 cites W1556151368 @default.
• W185280793 cites W1559484948 @default.
• W185280793 cites W1591586450 @default.
• W185280793 cites W1595143412 @default.
• W185280793 cites W1789486470 @default.
• W185280793 cites W187556099 @default.
• W185280793 cites W1958193080 @default.
• W185280793 cites W1959107903 @default.
• W185280793 cites W1966621021 @default.
• W185280793 cites W1966847603 @default.
• W185280793 cites W1969085733 @default.
• W185280793 cites W1971656494 @default.
• W185280793 cites W1971869828 @default.
• W185280793 cites W1972226511 @default.
• W185280793 cites W1972987136 @default.
• W185280793 cites W1973517467 @default.
• W185280793 cites W1975862779 @default.
• W185280793 cites W1977157092 @default.
• W185280793 cites W1978242698 @default.
• W185280793 cites W1980561488 @default.
• W185280793 cites W1981317595 @default.
• W185280793 cites W1981804411 @default.
• W185280793 cites W1982109771 @default.
• W185280793 cites W1983166974 @default.
• W185280793 cites W1985115233 @default.
• W185280793 cites W1986604740 @default.
• W185280793 cites W1987208383 @default.
• W185280793 cites W1990097831 @default.
• W185280793 cites W1990478369 @default.
• W185280793 cites W1991920880 @default.
• W185280793 cites W1994005628 @default.
• W185280793 cites W1997031088 @default.
• W185280793 cites W1997054434 @default.
• W185280793 cites W2006907494 @default.
• W185280793 cites W2010191085 @default.
• W185280793 cites W2010550077 @default.
• W185280793 cites W2012747241 @default.
• W185280793 cites W2012929536 @default.
• W185280793 cites W2016362976 @default.
• W185280793 cites W2016846569 @default.
• W185280793 cites W2017508534 @default.
• W185280793 cites W2018674823 @default.
• W185280793 cites W2019289959 @default.
• W185280793 cites W202811822 @default.
• W185280793 cites W2029738096 @default.
• W185280793 cites W2040337718 @default.
• W185280793 cites W2041368985 @default.
• W185280793 cites W2047747212 @default.
• W185280793 cites W2048930535 @default.
• W185280793 cites W2050985097 @default.
• W185280793 cites W2053497482 @default.
• W185280793 cites W2056850109 @default.
• W185280793 cites W2059534306 @default.
• W185280793 cites W2060749908 @default.
• W185280793 cites W2061882623 @default.
• W185280793 cites W2063498881 @default.
• W185280793 cites W2065549220 @default.
• W185280793 cites W2065577646 @default.
• W185280793 cites W2066406514 @default.
• W185280793 cites W2068382284 @default.
• W185280793 cites W2068908743 @default.
• W185280793 cites W2069978012 @default.
• W185280793 cites W2075231584 @default.
• W185280793 cites W2077147171 @default.
• W185280793 cites W2077282947 @default.
• W185280793 cites W2079165129 @default.
• W185280793 cites W2079734790 @default.
• W185280793 cites W2080376404 @default.
• W185280793 cites W2085083810 @default.
• W185280793 cites W2106045733 @default.
• W185280793 cites W2106279767 @default.
• W185280793 cites W2120654892 @default.
• W185280793 cites W2127077870 @default.
• W185280793 cites W2144001425 @default.
• W185280793 cites W2144795074 @default.
• W185280793 cites W2154037033 @default.
• W185280793 cites W2155858935 @default.
• W185280793 cites W2157432457 @default.
• W185280793 cites W2157534399 @default.
• W185280793 cites W2161315957 @default.
• W185280793 cites W2164228466 @default.
• W185280793 cites W2260618113 @default.

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