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- W1853642859 abstract "Good news from Emanuel and colleagues1—apparently, phase I clinical drug trials are safe. However, given the very low frequencies of serious adverse events, retrospective associations of trial characteristics with adverse events are of no use for predicting safety problems in future trials. None of these associations would have helped prevent the cytokine storm caused by TGN1412. This drug’s risk …" @default.
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- W1853642859 date "2015-07-22" @default.
- W1853642859 modified "2023-09-23" @default.
- W1853642859 title "Need for a proactive and structured approach to risk analysis when designing phase I trials" @default.
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- W1853642859 doi "https://doi.org/10.1136/bmj.h3899" @default.
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