Matches in SemOpenAlex for { <https://semopenalex.org/work/W1855229877> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W1855229877 endingPage "774" @default.
- W1855229877 startingPage "769" @default.
- W1855229877 abstract "Gallic acid (GA) is a common part of the human diet, both in the free form and as a metabolite of tannic acid and propyl gallate. Cell cultures were incubated with mixtures of either GA and beta interferon (IFN-beta) (formerly fibroblast IFN) or medium and IFN-beta. The cells were subsequently challenged with virus. The virus plaque yields were greater in cells incubated with IFN-beta and GA than in cells incubated with IFN-beta and medium, indicating that in the former mixture, IFN-beta had lost antiviral activity. The magnitude of the loss was dependent upon the GA concentration. IFN-alpha and IFN-gamma (formerly leukocyte IFN and immune IFN, respectively) were not similarly affected. The effect of GA on IFN-beta could be reversed with 2-mercaptoethanol, suggesting a possible sulfhydryl involvement. Extensive dialysis of IFN-beta-GA mixtures to remove the GA failed to reverse the reduction in antiviral activity. This suggests that a direct and irreversible interaction between IFN-beta and GA took place, reducing the activity of IFN-beta. The significance of this finding with regard to virus infections of the intestine is discussed." @default.
- W1855229877 created "2016-06-24" @default.
- W1855229877 creator A5006910766 @default.
- W1855229877 creator A5064277983 @default.
- W1855229877 creator A5068425391 @default.
- W1855229877 date "1981-09-01" @default.
- W1855229877 modified "2023-09-26" @default.
- W1855229877 title "Reduction in antiviral activity of human beta interferon by gallic acid" @default.
- W1855229877 cites W1777366304 @default.
- W1855229877 cites W1977341001 @default.
- W1855229877 cites W1984300797 @default.
- W1855229877 cites W2055992838 @default.
- W1855229877 cites W2057497221 @default.
- W1855229877 cites W2062531163 @default.
- W1855229877 cites W2066595148 @default.
- W1855229877 cites W2092713296 @default.
- W1855229877 cites W2148709869 @default.
- W1855229877 cites W2163577620 @default.
- W1855229877 cites W2320325538 @default.
- W1855229877 cites W2325858234 @default.
- W1855229877 cites W2559352041 @default.
- W1855229877 cites W4213051138 @default.
- W1855229877 doi "https://doi.org/10.1128/iai.33.3.769-774.1981" @default.
- W1855229877 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/350776" @default.
- W1855229877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6169644" @default.
- W1855229877 hasPublicationYear "1981" @default.
- W1855229877 type Work @default.
- W1855229877 sameAs 1855229877 @default.
- W1855229877 citedByCount "5" @default.
- W1855229877 countsByYear W18552298772012 @default.
- W1855229877 countsByYear W18552298772020 @default.
- W1855229877 crossrefType "journal-article" @default.
- W1855229877 hasAuthorship W1855229877A5006910766 @default.
- W1855229877 hasAuthorship W1855229877A5064277983 @default.
- W1855229877 hasAuthorship W1855229877A5068425391 @default.
- W1855229877 hasBestOaLocation W18552298771 @default.
- W1855229877 hasConcept C129437159 @default.
- W1855229877 hasConcept C136449434 @default.
- W1855229877 hasConcept C153911025 @default.
- W1855229877 hasConcept C159047783 @default.
- W1855229877 hasConcept C199360897 @default.
- W1855229877 hasConcept C203014093 @default.
- W1855229877 hasConcept C2522874641 @default.
- W1855229877 hasConcept C2776174256 @default.
- W1855229877 hasConcept C2776178377 @default.
- W1855229877 hasConcept C2778004101 @default.
- W1855229877 hasConcept C2778362808 @default.
- W1855229877 hasConcept C2780841837 @default.
- W1855229877 hasConcept C41008148 @default.
- W1855229877 hasConcept C55493867 @default.
- W1855229877 hasConcept C86803240 @default.
- W1855229877 hasConcept C8891405 @default.
- W1855229877 hasConceptScore W1855229877C129437159 @default.
- W1855229877 hasConceptScore W1855229877C136449434 @default.
- W1855229877 hasConceptScore W1855229877C153911025 @default.
- W1855229877 hasConceptScore W1855229877C159047783 @default.
- W1855229877 hasConceptScore W1855229877C199360897 @default.
- W1855229877 hasConceptScore W1855229877C203014093 @default.
- W1855229877 hasConceptScore W1855229877C2522874641 @default.
- W1855229877 hasConceptScore W1855229877C2776174256 @default.
- W1855229877 hasConceptScore W1855229877C2776178377 @default.
- W1855229877 hasConceptScore W1855229877C2778004101 @default.
- W1855229877 hasConceptScore W1855229877C2778362808 @default.
- W1855229877 hasConceptScore W1855229877C2780841837 @default.
- W1855229877 hasConceptScore W1855229877C41008148 @default.
- W1855229877 hasConceptScore W1855229877C55493867 @default.
- W1855229877 hasConceptScore W1855229877C86803240 @default.
- W1855229877 hasConceptScore W1855229877C8891405 @default.
- W1855229877 hasIssue "3" @default.
- W1855229877 hasLocation W18552298771 @default.
- W1855229877 hasLocation W18552298772 @default.
- W1855229877 hasLocation W18552298773 @default.
- W1855229877 hasOpenAccess W1855229877 @default.
- W1855229877 hasPrimaryLocation W18552298771 @default.
- W1855229877 hasRelatedWork W1855229877 @default.
- W1855229877 hasRelatedWork W1973676625 @default.
- W1855229877 hasRelatedWork W2055132694 @default.
- W1855229877 hasRelatedWork W2076610816 @default.
- W1855229877 hasRelatedWork W2082650872 @default.
- W1855229877 hasRelatedWork W2096468146 @default.
- W1855229877 hasRelatedWork W2136046700 @default.
- W1855229877 hasRelatedWork W2151702506 @default.
- W1855229877 hasRelatedWork W2153203193 @default.
- W1855229877 hasRelatedWork W2409379069 @default.
- W1855229877 hasVolume "33" @default.
- W1855229877 isParatext "false" @default.
- W1855229877 isRetracted "false" @default.
- W1855229877 magId "1855229877" @default.
- W1855229877 workType "article" @default.