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• W1855444711 startingPage "379" @default.
• W1855444711 abstract "Abstract To elucidate the nature of structural alterations in plants, three carbon ion-induced mutations in Arabidopsis thaliana, gl1-3, tt4(C1), and ttg1-21, were analyzed. The gl1-3 mutation was found to be generated by an inversion of a fragment that contained GL1 and Atpk7 loci on chromosome 3. The size of the inverted fragment was a few hundred kilobase pairs. The inversion was found to accompany an insertion of a 107-bp fragment derived from chromosome 2. The tt4(C1) mutation was also found to be due to an inversion. The size of the intervening region between the breakpoints was also estimated to be a few hundred kilobase pairs. In the case of ttg1-21, it was found that a break occurred at the TTG1 locus on chromosome 5, and reciprocal translocation took place between it and chromosome 3. From the sequences flanking the breakpoints, the DNA strand breaks induced by carbon ions were found to be rejoined using, if present, only short homologous sequences. Small deletions were also observed around the breakpoints. These results suggest that the nonhomologous end-joining (NHEJ) pathway operates after plant cells are exposed to ion particles." @default.
• W1855444711 created "2016-06-24" @default.
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• W1855444711 date "2001-01-01" @default.
• W1855444711 modified "2023-10-15" @default.
• W1855444711 title "Rearrangements of the DNA in Carbon Ion-Induced Mutants of <i>Arabidopsis thaliana</i>" @default.
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• W1855444711 doi "https://doi.org/10.1093/genetics/157.1.379" @default.
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