Matches in SemOpenAlex for { <https://semopenalex.org/work/W1855456072> ?p ?o ?g. }
- W1855456072 endingPage "66" @default.
- W1855456072 startingPage "56" @default.
- W1855456072 abstract "Habituation to repetitive noxious stimuli is a well-known phenomenon. We investigated brain correlates of habituation to pain in a transdermal electrical pain model using functional magnetic resonance imaging (fMRI).Electrical painful stimulation with 1 Hz was applied to the volar forearm of 48 healthy subjects for 45 min. Before and after conditioning stimulation, psychophysical testing and fMRI were performed. During fMRI sessions, the subjects underwent blockwise painful electrical stimulation with a fixed percept-adapted current intensity. After fMRI 1 and fMRI 2 subjects rated the individual pain intensity of the electrical stimulus.Substantial habituation occurred during conditioning electrical stimulation. Accordingly, areas typically involved in pain processing showed decreased activity after conditioning stimulation. The blood oxygen level-dependent signal of the subgenual anterior cingulate gyrus, the superior parietal lobule and the supplemental motor area correlated positively with habituation. In contrast, activity in the periaqueductal grey, thalamus and insula correlated negatively. The results of the correlation analyses did not survive correction for multiple comparisons.With this study, we identified central components associated with habituation to repetitive painful stimuli. The results suggest that an increase in tonic inhibitory activity in cortical pain processing areas is a major mechanism contributing to habituation to phasic noxious stimuli. Moreover, areas involved in descending pain modulation were differentially modulated. This may hint at a simultaneous activation of facilitating and inhibiting nociceptive systems that are both altered in the transdermal electrical pain model." @default.
- W1855456072 created "2016-06-24" @default.
- W1855456072 creator A5015953298 @default.
- W1855456072 creator A5033348686 @default.
- W1855456072 creator A5043619968 @default.
- W1855456072 creator A5050558735 @default.
- W1855456072 creator A5054809346 @default.
- W1855456072 creator A5058858179 @default.
- W1855456072 creator A5060376366 @default.
- W1855456072 date "2013-05-29" @default.
- W1855456072 modified "2023-10-08" @default.
- W1855456072 title "Brain correlates of short-term habituation to repetitive electrical noxious stimulation" @default.
- W1855456072 cites W1584957869 @default.
- W1855456072 cites W1988588117 @default.
- W1855456072 cites W2003102568 @default.
- W1855456072 cites W2003179105 @default.
- W1855456072 cites W2003288939 @default.
- W1855456072 cites W2004323875 @default.
- W1855456072 cites W2012145421 @default.
- W1855456072 cites W2014779151 @default.
- W1855456072 cites W2015734868 @default.
- W1855456072 cites W2017480274 @default.
- W1855456072 cites W2021353199 @default.
- W1855456072 cites W2023637680 @default.
- W1855456072 cites W2024656033 @default.
- W1855456072 cites W2025513503 @default.
- W1855456072 cites W2025577666 @default.
- W1855456072 cites W2032765281 @default.
- W1855456072 cites W2046017277 @default.
- W1855456072 cites W2053718871 @default.
- W1855456072 cites W2055606598 @default.
- W1855456072 cites W2059566520 @default.
- W1855456072 cites W2061350749 @default.
- W1855456072 cites W2062700118 @default.
- W1855456072 cites W2068949066 @default.
- W1855456072 cites W2075075486 @default.
- W1855456072 cites W2080745413 @default.
- W1855456072 cites W2086340015 @default.
- W1855456072 cites W2090772977 @default.
- W1855456072 cites W2093459270 @default.
- W1855456072 cites W2108944093 @default.
- W1855456072 cites W2111609296 @default.
- W1855456072 cites W2116064885 @default.
- W1855456072 cites W2128692107 @default.
- W1855456072 cites W2138191097 @default.
- W1855456072 cites W2138512124 @default.
- W1855456072 cites W2139510046 @default.
- W1855456072 cites W2141678708 @default.
- W1855456072 cites W2151225301 @default.
- W1855456072 cites W2158847210 @default.
- W1855456072 cites W2159334079 @default.
- W1855456072 cites W2160938249 @default.
- W1855456072 cites W2169539334 @default.
- W1855456072 cites W2254926144 @default.
- W1855456072 cites W2273923419 @default.
- W1855456072 cites W2298871813 @default.
- W1855456072 doi "https://doi.org/10.1002/j.1532-2149.2013.00339.x" @default.
- W1855456072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23720364" @default.
- W1855456072 hasPublicationYear "2013" @default.
- W1855456072 type Work @default.
- W1855456072 sameAs 1855456072 @default.
- W1855456072 citedByCount "22" @default.
- W1855456072 countsByYear W18554560722013 @default.
- W1855456072 countsByYear W18554560722014 @default.
- W1855456072 countsByYear W18554560722015 @default.
- W1855456072 countsByYear W18554560722016 @default.
- W1855456072 countsByYear W18554560722017 @default.
- W1855456072 countsByYear W18554560722018 @default.
- W1855456072 countsByYear W18554560722019 @default.
- W1855456072 countsByYear W18554560722020 @default.
- W1855456072 countsByYear W18554560722021 @default.
- W1855456072 countsByYear W18554560722022 @default.
- W1855456072 crossrefType "journal-article" @default.
- W1855456072 hasAuthorship W1855456072A5015953298 @default.
- W1855456072 hasAuthorship W1855456072A5033348686 @default.
- W1855456072 hasAuthorship W1855456072A5043619968 @default.
- W1855456072 hasAuthorship W1855456072A5050558735 @default.
- W1855456072 hasAuthorship W1855456072A5054809346 @default.
- W1855456072 hasAuthorship W1855456072A5058858179 @default.
- W1855456072 hasAuthorship W1855456072A5060376366 @default.
- W1855456072 hasConcept C104211972 @default.
- W1855456072 hasConcept C104996578 @default.
- W1855456072 hasConcept C126322002 @default.
- W1855456072 hasConcept C15490471 @default.
- W1855456072 hasConcept C15744967 @default.
- W1855456072 hasConcept C169760540 @default.
- W1855456072 hasConcept C170493617 @default.
- W1855456072 hasConcept C24998067 @default.
- W1855456072 hasConcept C2779144063 @default.
- W1855456072 hasConcept C2779226451 @default.
- W1855456072 hasConcept C2779918689 @default.
- W1855456072 hasConcept C2781069035 @default.
- W1855456072 hasConcept C50610925 @default.
- W1855456072 hasConcept C529278444 @default.
- W1855456072 hasConcept C542102704 @default.
- W1855456072 hasConcept C552161191 @default.
- W1855456072 hasConcept C71331990 @default.
- W1855456072 hasConcept C71924100 @default.