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• W1855844098 abstract "Biophysical properties of delayed rectifier K channels in the human neuroblastoma SH-SY5Y were established using patch clamp recordings. The whole cell K+ conductance activated at membrane potentials positive to -20 mV. The midpoint of current activation was 9.6 +/- 5.1 mV, the equivalent charge was 3.7 +/-.6. Whole-cell currents inactivated slightly with time constants of 700 ms and 5 s. The K+ currents were sensitive to micromolar concentrations of TEA and 4-aminopyridine. RT-PCR experiments amplified a cDNA fragment specific for human Kv3.1 channels. Activation gating parameters in outside-out patches were shifted by approximately 14 mV in the hyperpolarizing direction." @default.
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• W1855844098 date "2003-01-01" @default.
• W1855844098 modified "2023-10-16" @default.
• W1855844098 title "Biophysical Properties of Kv3.1 Channels in SH-SY5Y Human Neuroblastoma Cells" @default.
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• W1855844098 doi "https://doi.org/10.3109/714041019" @default.
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