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- W1857615512 abstract "Microwave (MW) irradiation facilitated synthesis provides fast, safe, simple, and green reaction conditions. MW irradiation of 2-aminobenzophenones with heteroaromatic ketones afforded quinolines via Friedlander condensation in high yields with intact halogen substituents for further modifications. Dibenzo[b,f][1,5]diazocines were found as minor products and in some instances as the only products as the result of self-condensation of 2-aminobenzophenones. Different acid catalysts were found to affect these cyclization processes. Mini library of quinolines and dibenzo[b,f][1,5]diazocines were created in order to understand the substituents effect on the reaction. Resultant quinolines and dibenzo[b,f][1,5]diazocines are anticipated to serve as an interesting library for high throughput screening of various biological applications." @default.
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- W1857615512 date "2015-10-09" @default.
- W1857615512 modified "2023-10-04" @default.
- W1857615512 title "Quinolines Formation by Condensation of Heteroaromatic Ketones and 2-Aminobenzophenones under MW Irradiation" @default.
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- W1857615512 doi "https://doi.org/10.1002/bkcs.10557" @default.
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