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• W1857691310 abstract "Highly enantioselective catalytic asymmetric intramolecular cascade imidization-nucleophilic addition-lactamization of N(1)-alkylethane-1,2-diamine with methyl 2-formylbenzoate catalyzed by a chiral phosphoric acid represents the first efficient method for the preparation of medicinally interesting chiral 2,3-dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-ones with high yields and excellent enantioselectivities. This strategy has been shown to be quite general toward various methyl 2-formylbenzoates." @default.
• W1857691310 created "2016-06-24" @default.
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• W1857691310 date "2014-12-03" @default.
• W1857691310 modified "2023-10-16" @default.
• W1857691310 title "Highly Enantioselective Synthesis of 2,3-Dihydro-1<i>H</i>-imidazo[2,1-<i>a</i>]isoindol-5(9b<i>H</i>)-ones via Catalytic Asymmetric Intramolecular Cascade Imidization–Nucleophilic Addition–Lactamization" @default.
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• W1857691310 doi "https://doi.org/10.1021/ol5031603" @default.
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• W1857691310 hasPublicationYear "2014" @default.
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