FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1857757680> ?p ?o ?g. }

• W1857757680 endingPage "88" @default.
• W1857757680 startingPage "82" @default.
• W1857757680 abstract "The study was to assess the long-term toxic effects of acetochlor on rats. Two different doses (42.96 and 107.4 mg/kg body weight/day) of acetochlor were administered to Wistar rats through their food for over 24 weeks. Rat urine samples were collected at two time-points for the measurements of the metabonomics profiles with ultra-performance liquid chromatography-mass spectrometry (UPLC-MSMS). The results of clinical chemistry and histopathology suggested that long-term use of acetochlor in rats caused liver and kidney damage, and dysfunction of antioxidant system. The urinary metabonomics analysis indicated that the high and low-dose exposure of acetochlor could cause alterations of these metabonomics in urine in the rat. Significant changes of the levels of hippuric acid (0.403-fold decrease), citric acid (0.430-fold decrease), pantothenic acid (0.486-fold decrease), uracil (0.419-fold decrease), β-Alanine (0.325-fold decrease), nonanedioic acid (0.445-fold decrease), L-tyrosine (0.410-fold decrease), D-glucuronic acid (8.389-fold increase) and 2-ethyl-6-methyl-N-methyl-2-chloro-acetanilide in urine were observed. In addition, it may interfere with the fatty acid synthesis, the pyrimidine degradation and pantothenate biosynthesis. The level of 2-ethyl-6-methyl-N-methyl-2-chloro-acetanilide is detected in all treated groups which is not found in the control groups, indicating which can be used as an early, sensitive marker of acetochlor exposure in rat. This study illustrates the important utility of metabonomics approaches to understand the toxicity of long-term exposure of acetochlor." @default.
• W1857757680 created "2016-06-24" @default.
• W1857757680 creator A5010187139 @default.
• W1857757680 creator A5018342823 @default.
• W1857757680 creator A5027541123 @default.
• W1857757680 creator A5032003836 @default.
• W1857757680 creator A5043071660 @default.
• W1857757680 creator A5056101043 @default.
• W1857757680 creator A5084942945 @default.
• W1857757680 date "2016-03-01" @default.
• W1857757680 modified "2023-10-17" @default.
• W1857757680 title "A urinary metabonomics analysis of long-term effect of acetochlor exposure on rats by ultra-performance liquid chromatography/mass spectrometry" @default.
• W1857757680 cites W1492675644 @default.
• W1857757680 cites W164263380 @default.
• W1857757680 cites W1918507985 @default.
• W1857757680 cites W1968813633 @default.
• W1857757680 cites W1970709685 @default.
• W1857757680 cites W2002340588 @default.
• W1857757680 cites W2011348557 @default.
• W1857757680 cites W2027616495 @default.
• W1857757680 cites W2056907461 @default.
• W1857757680 cites W2062690710 @default.
• W1857757680 cites W2071717608 @default.
• W1857757680 cites W2077101890 @default.
• W1857757680 cites W2087671468 @default.
• W1857757680 cites W2092543837 @default.
• W1857757680 cites W2093588363 @default.
• W1857757680 cites W2095948376 @default.
• W1857757680 cites W2106580946 @default.
• W1857757680 cites W2134200851 @default.
• W1857757680 cites W2136679436 @default.
• W1857757680 cites W2149217711 @default.
• W1857757680 cites W2151216008 @default.
• W1857757680 cites W2164836659 @default.
• W1857757680 doi "https://doi.org/10.1016/j.pestbp.2015.09.013" @default.
• W1857757680 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26969444" @default.
• W1857757680 hasPublicationYear "2016" @default.
• W1857757680 type Work @default.
• W1857757680 sameAs 1857757680 @default.
• W1857757680 citedByCount "32" @default.
• W1857757680 countsByYear W18577576802016 @default.
• W1857757680 countsByYear W18577576802017 @default.
• W1857757680 countsByYear W18577576802018 @default.
• W1857757680 countsByYear W18577576802019 @default.
• W1857757680 countsByYear W18577576802020 @default.
• W1857757680 countsByYear W18577576802021 @default.
• W1857757680 countsByYear W18577576802022 @default.
• W1857757680 countsByYear W18577576802023 @default.
• W1857757680 crossrefType "journal-article" @default.
• W1857757680 hasAuthorship W1857757680A5010187139 @default.
• W1857757680 hasAuthorship W1857757680A5018342823 @default.
• W1857757680 hasAuthorship W1857757680A5027541123 @default.
• W1857757680 hasAuthorship W1857757680A5032003836 @default.
• W1857757680 hasAuthorship W1857757680A5043071660 @default.
• W1857757680 hasAuthorship W1857757680A5056101043 @default.
• W1857757680 hasAuthorship W1857757680A5084942945 @default.
• W1857757680 hasConcept C126322002 @default.
• W1857757680 hasConcept C161176658 @default.
• W1857757680 hasConcept C178790620 @default.
• W1857757680 hasConcept C179998833 @default.
• W1857757680 hasConcept C185592680 @default.
• W1857757680 hasConcept C2777476671 @default.
• W1857757680 hasConcept C2779543999 @default.
• W1857757680 hasConcept C2780026642 @default.
• W1857757680 hasConcept C2780548424 @default.
• W1857757680 hasConcept C29730261 @default.
• W1857757680 hasConcept C43617362 @default.
• W1857757680 hasConcept C55493867 @default.
• W1857757680 hasConcept C6557445 @default.
• W1857757680 hasConcept C71924100 @default.
• W1857757680 hasConcept C77411442 @default.
• W1857757680 hasConcept C86803240 @default.
• W1857757680 hasConcept C98274493 @default.
• W1857757680 hasConceptScore W1857757680C126322002 @default.
• W1857757680 hasConceptScore W1857757680C161176658 @default.
• W1857757680 hasConceptScore W1857757680C178790620 @default.
• W1857757680 hasConceptScore W1857757680C179998833 @default.
• W1857757680 hasConceptScore W1857757680C185592680 @default.
• W1857757680 hasConceptScore W1857757680C2777476671 @default.
• W1857757680 hasConceptScore W1857757680C2779543999 @default.
• W1857757680 hasConceptScore W1857757680C2780026642 @default.
• W1857757680 hasConceptScore W1857757680C2780548424 @default.
• W1857757680 hasConceptScore W1857757680C29730261 @default.
• W1857757680 hasConceptScore W1857757680C43617362 @default.
• W1857757680 hasConceptScore W1857757680C55493867 @default.
• W1857757680 hasConceptScore W1857757680C6557445 @default.
• W1857757680 hasConceptScore W1857757680C71924100 @default.
• W1857757680 hasConceptScore W1857757680C77411442 @default.
• W1857757680 hasConceptScore W1857757680C86803240 @default.
• W1857757680 hasConceptScore W1857757680C98274493 @default.
• W1857757680 hasFunder F4320321001 @default.
• W1857757680 hasLocation W18577576801 @default.
• W1857757680 hasLocation W18577576802 @default.
• W1857757680 hasOpenAccess W1857757680 @default.
• W1857757680 hasPrimaryLocation W18577576801 @default.
• W1857757680 hasRelatedWork W118183763 @default.
• W1857757680 hasRelatedWork W1970888742 @default.
• W1857757680 hasRelatedWork W1986424816 @default.

• next