FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1857938673> ?p ?o ?g. }

• W1857938673 endingPage "428" @default.
• W1857938673 startingPage "419" @default.
• W1857938673 abstract "In this work we grafted vinyl- and azido-terminated tetrahydroisoquinolines (compounds 1 and 2, respectively) onto HSi(1 1 1) silicon wafers obtaining highly stable modified surfaces. A double bond was incorporated into the tetrahydroisoquinoline structure of 1 to be immobilized by a light induced hydrosilylation reaction on hydrogen-terminated Si(1 1 1). The best results were obtained employing a polar solvent (DMSO), rather than a non-polar solvent (toluene). The azide derivative 2 was grafted onto alkenyl-terminated silicon substrates with copper-catalyzed azide-alkyne cycloaddition (CuAAC). Atomic force microscopy (AFM), contact angle goniometry (CA) and X-ray photoemission spectroscopy (XPS) were used to demonstrate the incorporation of 1 and 2 into the surfaces, study the morphology of the modified surfaces and to calculate the yield of grafting and surface coverage. CA measurements showed the increase in the surface hydrophobicity when 1 or 2 were incorporated into the surface. Moreover, compounds 1 and 2 were prepared starting from 1-(p-nitrophenyl)tetrahydroisoquinoline 3 under smooth conditions and in good yields. The structures of 1 and 2 were designed with a reduced A-ring, two substituents at positions C-6 and C-7, an N-methyl group and a phenyl moiety at C-1 in order to provide a high affinity against dopaminergic receptors. Moreover, O-demethylation of 1 was carried out once it was adsorbed onto the surface by treatment with BBr3. The method presented constitutes a simple, easily reproducible and high yielding approach for grafting complex organic biomolecules with dopaminergic properties onto silicon surfaces." @default.
• W1857938673 created "2016-06-24" @default.
• W1857938673 creator A5000110137 @default.
• W1857938673 creator A5012582147 @default.
• W1857938673 creator A5025867873 @default.
• W1857938673 creator A5033580717 @default.
• W1857938673 creator A5059058549 @default.
• W1857938673 creator A5067801058 @default.
• W1857938673 creator A5084264883 @default.
• W1857938673 date "2016-01-01" @default.
• W1857938673 modified "2023-10-02" @default.
• W1857938673 title "Silicon surface biofunctionalization with dopaminergic tetrahydroisoquinoline derivatives" @default.
• W1857938673 cites W1925492557 @default.
• W1857938673 cites W1964396362 @default.
• W1857938673 cites W1965019300 @default.
• W1857938673 cites W1973902558 @default.
• W1857938673 cites W1976155817 @default.
• W1857938673 cites W1978093886 @default.
• W1857938673 cites W1982703698 @default.
• W1857938673 cites W1984796926 @default.
• W1857938673 cites W1988072340 @default.
• W1857938673 cites W1989602219 @default.
• W1857938673 cites W1993177131 @default.
• W1857938673 cites W1993231427 @default.
• W1857938673 cites W1993570407 @default.
• W1857938673 cites W1998811457 @default.
• W1857938673 cites W2004200115 @default.
• W1857938673 cites W2004285059 @default.
• W1857938673 cites W2010775082 @default.
• W1857938673 cites W2013516496 @default.
• W1857938673 cites W2013568732 @default.
• W1857938673 cites W2014811553 @default.
• W1857938673 cites W2017354752 @default.
• W1857938673 cites W2017700424 @default.
• W1857938673 cites W2022265330 @default.
• W1857938673 cites W2023557482 @default.
• W1857938673 cites W2023706718 @default.
• W1857938673 cites W2024724618 @default.
• W1857938673 cites W2027670638 @default.
• W1857938673 cites W2040905203 @default.
• W1857938673 cites W2043288385 @default.
• W1857938673 cites W2045381270 @default.
• W1857938673 cites W2050138771 @default.
• W1857938673 cites W2051570820 @default.
• W1857938673 cites W2057393780 @default.
• W1857938673 cites W2073555188 @default.
• W1857938673 cites W2076529491 @default.
• W1857938673 cites W2086535142 @default.
• W1857938673 cites W2088659758 @default.
• W1857938673 cites W2089231026 @default.
• W1857938673 cites W2092716816 @default.
• W1857938673 cites W2093321575 @default.
• W1857938673 cites W2093786378 @default.
• W1857938673 cites W2114004602 @default.
• W1857938673 cites W2124038639 @default.
• W1857938673 cites W2125309913 @default.
• W1857938673 cites W2150821353 @default.
• W1857938673 cites W2165286214 @default.
• W1857938673 cites W2165913719 @default.
• W1857938673 cites W2170124192 @default.
• W1857938673 doi "https://doi.org/10.1016/j.apsusc.2015.10.195" @default.
• W1857938673 hasPublicationYear "2016" @default.
• W1857938673 type Work @default.
• W1857938673 sameAs 1857938673 @default.
• W1857938673 citedByCount "11" @default.
• W1857938673 countsByYear W18579386732016 @default.
• W1857938673 countsByYear W18579386732017 @default.
• W1857938673 countsByYear W18579386732018 @default.
• W1857938673 countsByYear W18579386732019 @default.
• W1857938673 crossrefType "journal-article" @default.
• W1857938673 hasAuthorship W1857938673A5000110137 @default.
• W1857938673 hasAuthorship W1857938673A5012582147 @default.
• W1857938673 hasAuthorship W1857938673A5025867873 @default.
• W1857938673 hasAuthorship W1857938673A5033580717 @default.
• W1857938673 hasAuthorship W1857938673A5059058549 @default.
• W1857938673 hasAuthorship W1857938673A5067801058 @default.
• W1857938673 hasAuthorship W1857938673A5084264883 @default.
• W1857938673 hasConcept C115537861 @default.
• W1857938673 hasConcept C127413603 @default.
• W1857938673 hasConcept C147789679 @default.
• W1857938673 hasConcept C159985019 @default.
• W1857938673 hasConcept C161790260 @default.
• W1857938673 hasConcept C175708663 @default.
• W1857938673 hasConcept C178790620 @default.
• W1857938673 hasConcept C185592680 @default.
• W1857938673 hasConcept C188027245 @default.
• W1857938673 hasConcept C192562407 @default.
• W1857938673 hasConcept C2778024649 @default.
• W1857938673 hasConcept C2778421718 @default.
• W1857938673 hasConcept C2779664164 @default.
• W1857938673 hasConcept C2780471494 @default.
• W1857938673 hasConcept C42360764 @default.
• W1857938673 hasConcept C544956773 @default.
• W1857938673 hasConcept C6556556 @default.
• W1857938673 hasConcept C75473681 @default.
• W1857938673 hasConceptScore W1857938673C115537861 @default.
• W1857938673 hasConceptScore W1857938673C127413603 @default.
• W1857938673 hasConceptScore W1857938673C147789679 @default.

• next