FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1858131419> ?p ?o ?g. }

• W1858131419 endingPage "3249" @default.
• W1858131419 startingPage "3244" @default.
• W1858131419 abstract "We previously reported that Candida albicans yeast cells adhere to the macrophage-rich medullary and subcapsular sinus areas of mouse lymph node tissue. To determine whether the yeast cell-lymph node interaction is mediated by macrophages, the effect of specific elimination of macrophages on yeast cell binding was studied, and yeast cell adherence was correlated with the ingestion of India ink by lymph node cells. Macrophage elimination was done by use of liposome-containing dichloromethylene diphosphonate (L-Cl2MDP). Mice were injected in the hind footpads with the L-Cl2MDP preparation, popliteal lymph nodes were removed 5 days later, and yeast cell adherence was determined by an ex vivo binding assay. As controls, lymph nodes from mice that received footpad injections of either phosphate-buffered saline (PBS) alone or liposome-containing PBS were used. Use of macrophage- and neutrophil-specific monoclonal antibodies in tissue immunostaining showed that the L-Cl2MDP treatment eliminated macrophages but not neutrophils from the medullary and subcapsular sinus areas of the popliteal lymph nodes. A striking reduction of yeast cell adherence occurred with lymph nodes from L-Cl2MDP-treated mice compared with lymph nodes from control animals. The lymph node-yeast cell binding patterns of L-Cl2MDP-treated and control mice were the same regardless of mouse strain, sex, or T-cell competency. Results of India ink experiments, in which India ink was injected into footpads of mice and was rapidly taken up by popliteal lymph node macrophages, showed a strong correlation between yeast adherence and India ink staining of cells. In addition, the interaction of yeast cells with lymph node tissue from normal mice was not significantly affected by the addition of two extracellular matrix proteins, fibronectin and laminin, during the ex vivo adherence assay. These data indicate that medullary and subcapsular sinus lymph node macrophages express an adhesion system similar to that described for mouse splenic marginal zone macrophages." @default.
• W1858131419 created "2016-06-24" @default.
• W1858131419 creator A5041105225 @default.
• W1858131419 creator A5078747529 @default.
• W1858131419 creator A5079003683 @default.
• W1858131419 date "1993-08-01" @default.
• W1858131419 modified "2023-09-24" @default.
• W1858131419 title "Binding of Candida albicans yeast cells to mouse popliteal lymph node tissue is mediated by macrophages" @default.
• W1858131419 cites W1515534695 @default.
• W1858131419 cites W1618054703 @default.
• W1858131419 cites W177593170 @default.
• W1858131419 cites W1806627819 @default.
• W1858131419 cites W1870010996 @default.
• W1858131419 cites W1880167351 @default.
• W1858131419 cites W1882829064 @default.
• W1858131419 cites W1890684887 @default.
• W1858131419 cites W1965384800 @default.
• W1858131419 cites W1972186370 @default.
• W1858131419 cites W1976339563 @default.
• W1858131419 cites W1998732462 @default.
• W1858131419 cites W2036251220 @default.
• W1858131419 cites W2039373027 @default.
• W1858131419 cites W2060301404 @default.
• W1858131419 cites W2065840171 @default.
• W1858131419 cites W2082825612 @default.
• W1858131419 cites W2089819283 @default.
• W1858131419 cites W2118075416 @default.
• W1858131419 cites W2130577876 @default.
• W1858131419 cites W2131260695 @default.
• W1858131419 cites W2135163402 @default.
• W1858131419 cites W2167519352 @default.
• W1858131419 cites W2168566305 @default.
• W1858131419 cites W2183796854 @default.
• W1858131419 cites W2270784779 @default.
• W1858131419 cites W2301676534 @default.
• W1858131419 cites W2314576442 @default.
• W1858131419 cites W2340373274 @default.
• W1858131419 cites W2400518925 @default.
• W1858131419 doi "https://doi.org/10.1128/iai.61.8.3244-3249.1993" @default.
• W1858131419 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/280995" @default.
• W1858131419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8335357" @default.
• W1858131419 hasPublicationYear "1993" @default.
• W1858131419 type Work @default.
• W1858131419 sameAs 1858131419 @default.
• W1858131419 citedByCount "19" @default.
• W1858131419 countsByYear W18581314192012 @default.
• W1858131419 crossrefType "journal-article" @default.
• W1858131419 hasAuthorship W1858131419A5041105225 @default.
• W1858131419 hasAuthorship W1858131419A5078747529 @default.
• W1858131419 hasAuthorship W1858131419A5079003683 @default.
• W1858131419 hasBestOaLocation W18581314191 @default.
• W1858131419 hasConcept C142724271 @default.
• W1858131419 hasConcept C153911025 @default.
• W1858131419 hasConcept C202751555 @default.
• W1858131419 hasConcept C203014093 @default.
• W1858131419 hasConcept C2779244956 @default.
• W1858131419 hasConcept C2779720271 @default.
• W1858131419 hasConcept C2780849966 @default.
• W1858131419 hasConcept C2780917455 @default.
• W1858131419 hasConcept C2780931953 @default.
• W1858131419 hasConcept C55493867 @default.
• W1858131419 hasConcept C71924100 @default.
• W1858131419 hasConcept C86803240 @default.
• W1858131419 hasConcept C89423630 @default.
• W1858131419 hasConceptScore W1858131419C142724271 @default.
• W1858131419 hasConceptScore W1858131419C153911025 @default.
• W1858131419 hasConceptScore W1858131419C202751555 @default.
• W1858131419 hasConceptScore W1858131419C203014093 @default.
• W1858131419 hasConceptScore W1858131419C2779244956 @default.
• W1858131419 hasConceptScore W1858131419C2779720271 @default.
• W1858131419 hasConceptScore W1858131419C2780849966 @default.
• W1858131419 hasConceptScore W1858131419C2780917455 @default.
• W1858131419 hasConceptScore W1858131419C2780931953 @default.
• W1858131419 hasConceptScore W1858131419C55493867 @default.
• W1858131419 hasConceptScore W1858131419C71924100 @default.
• W1858131419 hasConceptScore W1858131419C86803240 @default.
• W1858131419 hasConceptScore W1858131419C89423630 @default.
• W1858131419 hasIssue "8" @default.
• W1858131419 hasLocation W18581314191 @default.
• W1858131419 hasLocation W18581314192 @default.
• W1858131419 hasLocation W18581314193 @default.
• W1858131419 hasOpenAccess W1858131419 @default.
• W1858131419 hasPrimaryLocation W18581314191 @default.
• W1858131419 hasRelatedWork W1568820066 @default.
• W1858131419 hasRelatedWork W1575953077 @default.
• W1858131419 hasRelatedWork W1589532602 @default.
• W1858131419 hasRelatedWork W1983063915 @default.
• W1858131419 hasRelatedWork W1991963568 @default.
• W1858131419 hasRelatedWork W2034738051 @default.
• W1858131419 hasRelatedWork W2043153214 @default.
• W1858131419 hasRelatedWork W2056698445 @default.
• W1858131419 hasRelatedWork W2092050225 @default.
• W1858131419 hasRelatedWork W4290014795 @default.
• W1858131419 hasVolume "61" @default.
• W1858131419 isParatext "false" @default.
• W1858131419 isRetracted "false" @default.
• W1858131419 magId "1858131419" @default.
• W1858131419 workType "article" @default.