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• W1858237712 abstract "Aim: To evaluate the long-term effectiveness of rivastigmine patch or capsule on mild to severe Alzheimer’s disease (AD). Method: We performed a meta-analysis of 17 studies regarding the treatment effectiveness of rivastigmine patch or capsule on mild-to-severe AD. Results: Significant difference exists between treatment with rivastigmine patch or capsule and placebo groups (p-value < 0.001). In the Alzheimer’s Disease Assessment Scale-Cognitive subscale (ADAS-Cog) score evaluation, a negative weighted mean difference (WMD) was observed in overall and mild-moderate groups after rivastigmine treatment. And in ADAS-ADL score evaluation, a positive WMD was observed in overall groups after rivastigmine treatment. Moreover, WMD value is lower in patch administration subgroup compared to that of capsule administration subgroup. Conclusion: Rivastigmine treatment shows a positive result of improving the condition of patients with mild-to-severe AD. Patch administration shows a stronger effect on decreasing ADAS-Cog score compared to capsule administration." @default.
• W1858237712 created "2016-06-24" @default.
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• W1858237712 date "2015-08-06" @default.
• W1858237712 modified "2023-10-03" @default.
• W1858237712 title "Long-term effectiveness of rivastigmine patch or capsule for mild-to-severe Alzheimer’s disease: a meta-analysis" @default.
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• W1858237712 doi "https://doi.org/10.1586/14737175.2015.1068120" @default.
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