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- W1858379610 abstract "30 controls (healthy euthyroid volunteers) 31 pregnant patients (17-41 years; 12-40 weeks gestation) and 20 patients receiving oral contraceptives (OC) were tested to examine thyroid function. Serum was analyzed for total serum thyroxine T3-resin uptake throxine binding globulin (TBG) and thyroxine-binding prealbumin (TBPA) capacities by reverse flow paper electophoresis and thyroxine by equilibrium dialysis using a modification of the method of Ingbar et al. 24 hour thyroid uptake was measured in some controls and in OC patients. Free thyroxine index was calculated. The following results were obtained: 73% pregnant women and 35% OC patients had higher total serum thyroxine than controls (p<.01); the T3-resin uptake was lower in pregnant women (65%) and OC patients than controls (p<.01); 93% of pregnant women and 100% OC patients had higher TBG capacity than controls (p<.01); mean value of absolute thyroxine in pregnant women was significantly higher than controls (p<.01) and OC patients (p<.05) confirming the euthyroid clinical status of OC patients although there were overlapping individual values. The free thyroxine index was not reliable for testing small increases the 24-hour uptake of iodine-131 was normal in OC patients." @default.
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- W1858379610 date "1968-11-09" @default.
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- W1858379610 title "Effects of oral contraceptives and pregnancy on thyroid function." @default.
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