Matches in SemOpenAlex for { <https://semopenalex.org/work/W1858400559> ?p ?o ?g. }
- W1858400559 abstract "Publisher Summary This chapter deals with the origin and emergence of AIDS and briefly explains how HIV is closely related to simian immunodeficiency viruses (SIV) from nonhuman primates. The discovery of the first SIV, the SIVs in African nonhuman primates, pathogenicity of SIVs in their natural hosts and evolution and phylogeny of SIVs are explained. It explains how the HIV-1 is derived from SIVs circulating among African apes and reviews how SIVs from chimpanzees and gorillas are the ancestors of HIV-1 in humans. The ongoing exposure of humans to a large diversity of SIVs, exposures to SIV-infected primates, SIV prevalences and cross-species transmissions, viral adaptation and how human factors play a major role in the epidemic spread of a new virus, especially among viruses that are transmitted by blood or sexual contacts, as it is the case for HIV are discussed. It reviews how the ongoing cross-species transmissions from other retroviruses from primates to humans, the ongoing transmissions of SFV and STLV which emphasizes on the risk for potential emergence of a new SIV into the human population. The current HIV-1 epidemic provides evidence for the extraordinary impact that can result from a single primate lentiviral zoonotic transmission event. It concludes that while more insights are gained about the origin of the HIV-1 and HIV-2 viruses, there are some important questions concerning pathogenicity and epidemic spread of certain HIV/SIV variants which needs to be further elucidated." @default.
- W1858400559 created "2016-06-24" @default.
- W1858400559 creator A5048275896 @default.
- W1858400559 creator A5074518938 @default.
- W1858400559 creator A5080065932 @default.
- W1858400559 date "2017-01-01" @default.
- W1858400559 modified "2023-09-27" @default.
- W1858400559 title "Origin and Emergence of HIV/AIDS" @default.
- W1858400559 cites W1518187558 @default.
- W1858400559 cites W1762082768 @default.
- W1858400559 cites W1810629547 @default.
- W1858400559 cites W1961514588 @default.
- W1858400559 cites W1964981073 @default.
- W1858400559 cites W1967760575 @default.
- W1858400559 cites W1968838260 @default.
- W1858400559 cites W1969535318 @default.
- W1858400559 cites W1971882980 @default.
- W1858400559 cites W1974115977 @default.
- W1858400559 cites W1977282539 @default.
- W1858400559 cites W1987006995 @default.
- W1858400559 cites W1987888541 @default.
- W1858400559 cites W1989434432 @default.
- W1858400559 cites W1991038167 @default.
- W1858400559 cites W1991302498 @default.
- W1858400559 cites W1991528647 @default.
- W1858400559 cites W1992125446 @default.
- W1858400559 cites W1993170082 @default.
- W1858400559 cites W1998529967 @default.
- W1858400559 cites W1998906279 @default.
- W1858400559 cites W2002292720 @default.
- W1858400559 cites W2004045952 @default.
- W1858400559 cites W2004222410 @default.
- W1858400559 cites W2004669329 @default.
- W1858400559 cites W2005149743 @default.
- W1858400559 cites W2006315204 @default.
- W1858400559 cites W2008791719 @default.
- W1858400559 cites W2016581769 @default.
- W1858400559 cites W2017444339 @default.
- W1858400559 cites W2020927372 @default.
- W1858400559 cites W2021906926 @default.
- W1858400559 cites W2023079156 @default.
- W1858400559 cites W2023513435 @default.
- W1858400559 cites W2024702861 @default.
- W1858400559 cites W2025373690 @default.
- W1858400559 cites W2025509968 @default.
- W1858400559 cites W2027844128 @default.
- W1858400559 cites W2028753624 @default.
- W1858400559 cites W2030482575 @default.
- W1858400559 cites W2031830783 @default.
- W1858400559 cites W2034858284 @default.
- W1858400559 cites W2044916494 @default.
- W1858400559 cites W2047323802 @default.
- W1858400559 cites W2050489828 @default.
- W1858400559 cites W2052501406 @default.
- W1858400559 cites W2053373180 @default.
- W1858400559 cites W2054716809 @default.
- W1858400559 cites W2055224217 @default.
- W1858400559 cites W2059184131 @default.
- W1858400559 cites W2060382609 @default.
- W1858400559 cites W2060383804 @default.
- W1858400559 cites W2061344967 @default.
- W1858400559 cites W2063286219 @default.
- W1858400559 cites W2063465748 @default.
- W1858400559 cites W2065043268 @default.
- W1858400559 cites W2067001544 @default.
- W1858400559 cites W2068233660 @default.
- W1858400559 cites W2068253484 @default.
- W1858400559 cites W2069554621 @default.
- W1858400559 cites W2082034316 @default.
- W1858400559 cites W2084470763 @default.
- W1858400559 cites W2085015294 @default.
- W1858400559 cites W2089384420 @default.
- W1858400559 cites W2089840851 @default.
- W1858400559 cites W2092258010 @default.
- W1858400559 cites W2092866733 @default.
- W1858400559 cites W2094241145 @default.
- W1858400559 cites W2094726001 @default.
- W1858400559 cites W2096363667 @default.
- W1858400559 cites W2097231226 @default.
- W1858400559 cites W2098433844 @default.
- W1858400559 cites W2099311529 @default.
- W1858400559 cites W2102378887 @default.
- W1858400559 cites W2103139187 @default.
- W1858400559 cites W2104816728 @default.
- W1858400559 cites W2106245031 @default.
- W1858400559 cites W2108954360 @default.
- W1858400559 cites W2109100941 @default.
- W1858400559 cites W2109597614 @default.
- W1858400559 cites W2110538282 @default.
- W1858400559 cites W2111143795 @default.
- W1858400559 cites W2111776662 @default.
- W1858400559 cites W2112218396 @default.
- W1858400559 cites W2117044804 @default.
- W1858400559 cites W2117761852 @default.
- W1858400559 cites W2122502828 @default.
- W1858400559 cites W2123364760 @default.
- W1858400559 cites W2123563614 @default.
- W1858400559 cites W2123891648 @default.
- W1858400559 cites W2124409966 @default.
- W1858400559 cites W2124627199 @default.