FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1858463953> ?p ?o ?g. }

• W1858463953 endingPage "1412" @default.
• W1858463953 startingPage "1407" @default.
• W1858463953 abstract "To undertake a new protocol with the goals of improving the chemotherapeutic treatment of pediatric Ewing's sarcoma by introducing ifosfamide, and to widen the indications for surgical resection of Ewing's tumor to obtain better local control and to reduce radiation doses.The French Society of Pediatric Oncology initiated its first cooperative Ewing's sarcoma study in 1978, using a four-drug regimen (cyclophosphamide, dactinomycin, Adriamycin [doxorubicin; Farmitalia Carlo Erba, Rueil-Malmaison, France], and vincristine). Ninety-five patients were included, and, at 5 years, the disease-free survival reached a plateau of 51%. After encouraging responses of recurrent soft tissue or bone sarcomas to ifosfamide, a second study began in 1984 using a new chemotherapy regimen in which cyclophosphamide was replaced by ifosfamide. Sixty-five patients were treated.By February 1992, the median follow-up was 5.8 years. The estimated 5-year disease-free survival was 52%. We observed unexpected cardiac toxicity. Three patients experienced acute cardiac failure that was lethal in two cases. The acute toxicity of ifosfamide prompted us to stop the protocol. Retrospectively, the lack of efficacy reinforced our decision.We conclude that ifosfamide did not improve the outcome of the patients despite the fact that these two treatment regimens were not randomized." @default.
• W1858463953 created "2016-06-24" @default.
• W1858463953 creator A5005515833 @default.
• W1858463953 creator A5020593337 @default.
• W1858463953 creator A5021039464 @default.
• W1858463953 creator A5035528948 @default.
• W1858463953 creator A5037694078 @default.
• W1858463953 creator A5059228974 @default.
• W1858463953 creator A5061978362 @default.
• W1858463953 creator A5067218613 @default.
• W1858463953 creator A5080299344 @default.
• W1858463953 creator A5085088950 @default.
• W1858463953 date "1992-09-01" @default.
• W1858463953 modified "2023-09-24" @default.
• W1858463953 title "No benefit of ifosfamide in Ewing's sarcoma: a nonrandomized study of the French Society of Pediatric Oncology." @default.
• W1858463953 cites W1860950940 @default.
• W1858463953 cites W1870262831 @default.
• W1858463953 cites W1985018306 @default.
• W1858463953 cites W2002215328 @default.
• W1858463953 cites W2028800748 @default.
• W1858463953 cites W2053139581 @default.
• W1858463953 cites W2054587417 @default.
• W1858463953 cites W2056787996 @default.
• W1858463953 cites W2077317421 @default.
• W1858463953 cites W2123303774 @default.
• W1858463953 doi "https://doi.org/10.1200/jco.1992.10.9.1407" @default.
• W1858463953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1517783" @default.
• W1858463953 hasPublicationYear "1992" @default.
• W1858463953 type Work @default.
• W1858463953 sameAs 1858463953 @default.
• W1858463953 citedByCount "78" @default.
• W1858463953 countsByYear W18584639532013 @default.
• W1858463953 countsByYear W18584639532014 @default.
• W1858463953 countsByYear W18584639532015 @default.
• W1858463953 countsByYear W18584639532016 @default.
• W1858463953 countsByYear W18584639532017 @default.
• W1858463953 countsByYear W18584639532019 @default.
• W1858463953 countsByYear W18584639532021 @default.
• W1858463953 crossrefType "journal-article" @default.
• W1858463953 hasAuthorship W1858463953A5005515833 @default.
• W1858463953 hasAuthorship W1858463953A5020593337 @default.
• W1858463953 hasAuthorship W1858463953A5021039464 @default.
• W1858463953 hasAuthorship W1858463953A5035528948 @default.
• W1858463953 hasAuthorship W1858463953A5037694078 @default.
• W1858463953 hasAuthorship W1858463953A5059228974 @default.
• W1858463953 hasAuthorship W1858463953A5061978362 @default.
• W1858463953 hasAuthorship W1858463953A5067218613 @default.
• W1858463953 hasAuthorship W1858463953A5080299344 @default.
• W1858463953 hasAuthorship W1858463953A5085088950 @default.
• W1858463953 hasConcept C126322002 @default.
• W1858463953 hasConcept C141071460 @default.
• W1858463953 hasConcept C142724271 @default.
• W1858463953 hasConcept C143998085 @default.
• W1858463953 hasConcept C2776694085 @default.
• W1858463953 hasConcept C2776755627 @default.
• W1858463953 hasConcept C2777506904 @default.
• W1858463953 hasConcept C2777586341 @default.
• W1858463953 hasConcept C2778119113 @default.
• W1858463953 hasConcept C2778256501 @default.
• W1858463953 hasConcept C2778670039 @default.
• W1858463953 hasConcept C2779429289 @default.
• W1858463953 hasConcept C2781303535 @default.
• W1858463953 hasConcept C2781413609 @default.
• W1858463953 hasConcept C71924100 @default.
• W1858463953 hasConceptScore W1858463953C126322002 @default.
• W1858463953 hasConceptScore W1858463953C141071460 @default.
• W1858463953 hasConceptScore W1858463953C142724271 @default.
• W1858463953 hasConceptScore W1858463953C143998085 @default.
• W1858463953 hasConceptScore W1858463953C2776694085 @default.
• W1858463953 hasConceptScore W1858463953C2776755627 @default.
• W1858463953 hasConceptScore W1858463953C2777506904 @default.
• W1858463953 hasConceptScore W1858463953C2777586341 @default.
• W1858463953 hasConceptScore W1858463953C2778119113 @default.
• W1858463953 hasConceptScore W1858463953C2778256501 @default.
• W1858463953 hasConceptScore W1858463953C2778670039 @default.
• W1858463953 hasConceptScore W1858463953C2779429289 @default.
• W1858463953 hasConceptScore W1858463953C2781303535 @default.
• W1858463953 hasConceptScore W1858463953C2781413609 @default.
• W1858463953 hasConceptScore W1858463953C71924100 @default.
• W1858463953 hasIssue "9" @default.
• W1858463953 hasLocation W18584639531 @default.
• W1858463953 hasLocation W18584639532 @default.
• W1858463953 hasOpenAccess W1858463953 @default.
• W1858463953 hasPrimaryLocation W18584639531 @default.
• W1858463953 hasRelatedWork W1858463953 @default.
• W1858463953 hasRelatedWork W1952212414 @default.
• W1858463953 hasRelatedWork W1973158710 @default.
• W1858463953 hasRelatedWork W2019852837 @default.
• W1858463953 hasRelatedWork W2036082666 @default.
• W1858463953 hasRelatedWork W2059330875 @default.
• W1858463953 hasRelatedWork W2060816095 @default.
• W1858463953 hasRelatedWork W2128266953 @default.
• W1858463953 hasRelatedWork W2416566838 @default.
• W1858463953 hasRelatedWork W2993626081 @default.
• W1858463953 hasVolume "10" @default.
• W1858463953 isParatext "false" @default.
• W1858463953 isRetracted "false" @default.
• W1858463953 magId "1858463953" @default.

• next