FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1858648093> ?p ?o ?g. }

• W1858648093 endingPage "2642" @default.
• W1858648093 startingPage "2633" @default.
• W1858648093 abstract "Abstract The lateral septal area is rich in vasopressin V 1A receptors and is densely innervated by vasopressinergic axons, originating mainly from the bed nucleus of the stria terminalis and the amygdala. Genetic and behavioral studies provide evidence that activation of vasopressin receptors in this area plays a determinant role in promoting social recognition. What could be the neuronal mechanism underlying this effect? Using rat brain slices and whole‐cell recordings, we found that lateral septal neurons are under the influence of a basal GABAergic inhibitory input. Vasopressin, acting via V 1A but not V 1B receptors, greatly enhanced this input in nearly all neurons. The peptide had no effect on miniature inhibitory postsynaptic currents, indicating that it acted on receptors located in the somatodendritic membrane, rather than on axon terminals, of GABAergic interneurons. Cell‐attached recordings showed that vasopressin can cause a direct excitation of a subpopulation of lateral septal neurons by acting via V 1A but not V 1B receptors. The presence in the lateral septum of V 1A but not of V 1B receptors was confirmed by competition binding studies using light microscopic autoradiography. In conclusion, vasopressin appears to act in the lateral septum in a dual mode: (i) by causing a direct excitation of a subpopulation of neurons, and (ii) by causing an indirect inhibition of virtually all lateral septal neurons. This modulation by vasopressin of the lateral septal circuitry may be part of the neuronal mechanism by which the peptide, acting via V 1A receptors, promotes social recognition." @default.
• W1858648093 created "2016-06-24" @default.
• W1858648093 creator A5018685690 @default.
• W1858648093 creator A5029335871 @default.
• W1858648093 creator A5069698831 @default.
• W1858648093 creator A5090557399 @default.
• W1858648093 date "2007-10-26" @default.
• W1858648093 modified "2023-10-10" @default.
• W1858648093 title "Vasopressin modulates lateral septal network activity via two distinct electrophysiological mechanisms" @default.
• W1858648093 cites W1635412086 @default.
• W1858648093 cites W1964779574 @default.
• W1858648093 cites W1967950137 @default.
• W1858648093 cites W1969055814 @default.
• W1858648093 cites W1969530560 @default.
• W1858648093 cites W1970483019 @default.
• W1858648093 cites W1975731777 @default.
• W1858648093 cites W1978390724 @default.
• W1858648093 cites W1981333355 @default.
• W1858648093 cites W1988176673 @default.
• W1858648093 cites W1989768591 @default.
• W1858648093 cites W1992729034 @default.
• W1858648093 cites W1996368170 @default.
• W1858648093 cites W1998872047 @default.
• W1858648093 cites W2001060581 @default.
• W1858648093 cites W2002929896 @default.
• W1858648093 cites W2005215696 @default.
• W1858648093 cites W2022494716 @default.
• W1858648093 cites W2025845183 @default.
• W1858648093 cites W2030222681 @default.
• W1858648093 cites W2030547745 @default.
• W1858648093 cites W2031254814 @default.
• W1858648093 cites W2039413967 @default.
• W1858648093 cites W2049439762 @default.
• W1858648093 cites W2051623102 @default.
• W1858648093 cites W2055233360 @default.
• W1858648093 cites W2057355057 @default.
• W1858648093 cites W2058147277 @default.
• W1858648093 cites W2066724194 @default.
• W1858648093 cites W2085319220 @default.
• W1858648093 cites W2096700862 @default.
• W1858648093 cites W2104338110 @default.
• W1858648093 cites W2105602144 @default.
• W1858648093 cites W2112808874 @default.
• W1858648093 cites W2122615913 @default.
• W1858648093 cites W2132778679 @default.
• W1858648093 cites W2138559331 @default.
• W1858648093 cites W2144144293 @default.
• W1858648093 cites W2152744015 @default.
• W1858648093 cites W2162632863 @default.
• W1858648093 cites W4242549075 @default.
• W1858648093 doi "https://doi.org/10.1111/j.1460-9568.2007.05866.x" @default.
• W1858648093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17970727" @default.
• W1858648093 hasPublicationYear "2007" @default.
• W1858648093 type Work @default.
• W1858648093 sameAs 1858648093 @default.
• W1858648093 citedByCount "27" @default.
• W1858648093 countsByYear W18586480932012 @default.
• W1858648093 countsByYear W18586480932013 @default.
• W1858648093 countsByYear W18586480932014 @default.
• W1858648093 countsByYear W18586480932015 @default.
• W1858648093 countsByYear W18586480932017 @default.
• W1858648093 countsByYear W18586480932018 @default.
• W1858648093 countsByYear W18586480932019 @default.
• W1858648093 countsByYear W18586480932020 @default.
• W1858648093 countsByYear W18586480932021 @default.
• W1858648093 countsByYear W18586480932022 @default.
• W1858648093 countsByYear W18586480932023 @default.
• W1858648093 crossrefType "journal-article" @default.
• W1858648093 hasAuthorship W1858648093A5018685690 @default.
• W1858648093 hasAuthorship W1858648093A5029335871 @default.
• W1858648093 hasAuthorship W1858648093A5069698831 @default.
• W1858648093 hasAuthorship W1858648093A5090557399 @default.
• W1858648093 hasConcept C118303440 @default.
• W1858648093 hasConcept C134018914 @default.
• W1858648093 hasConcept C168258287 @default.
• W1858648093 hasConcept C169760540 @default.
• W1858648093 hasConcept C170493617 @default.
• W1858648093 hasConcept C17077164 @default.
• W1858648093 hasConcept C197341189 @default.
• W1858648093 hasConcept C2776370428 @default.
• W1858648093 hasConcept C2776885963 @default.
• W1858648093 hasConcept C2778652331 @default.
• W1858648093 hasConcept C2779144063 @default.
• W1858648093 hasConcept C2779530196 @default.
• W1858648093 hasConcept C2780148200 @default.
• W1858648093 hasConcept C55493867 @default.
• W1858648093 hasConcept C86803240 @default.
• W1858648093 hasConcept C90474776 @default.
• W1858648093 hasConceptScore W1858648093C118303440 @default.
• W1858648093 hasConceptScore W1858648093C134018914 @default.
• W1858648093 hasConceptScore W1858648093C168258287 @default.
• W1858648093 hasConceptScore W1858648093C169760540 @default.
• W1858648093 hasConceptScore W1858648093C170493617 @default.
• W1858648093 hasConceptScore W1858648093C17077164 @default.
• W1858648093 hasConceptScore W1858648093C197341189 @default.
• W1858648093 hasConceptScore W1858648093C2776370428 @default.
• W1858648093 hasConceptScore W1858648093C2776885963 @default.
• W1858648093 hasConceptScore W1858648093C2778652331 @default.

• next