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• W1858789728 abstract "Subjects with genital warts were immunized three times or more with HPV6b VLPs without adjuvant. All immunized subjects had DTH to HPV6b L1 protein. Of 32 subjects, nine had HPV6b specific antibody prior to immunization and 22 acquired antibody with immunization. VLP specific antibody increased following a single immunization in 6 of 8 subjects with low level antibody at recruitment. Complete regression of genital warts was observed in 25 of 33 evaluable subjects over the 20-week observation period. We conclude that immunization with HPV6b L1 VLPs without adjuvant induces immunity to the L1 protein epitopes recognised during natural infection, and may accelerate regression of warts." @default.
• W1858789728 created "2016-06-24" @default.
• W1858789728 creator A5051990530 @default.
• W1858789728 date "2000-01-06" @default.
• W1858789728 modified "2023-10-08" @default.
• W1858789728 title "HPV6b virus like particles are potent immunogens without adjuvant in man" @default.
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• W1858789728 doi "https://doi.org/10.1016/s0264-410x(99)00351-5" @default.
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