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• W1859347148 abstract "ABSTRACT The control of the cell cycle is dependent on the ability to synthesize and degrade proteins called cyclins. When antisense oligonucleotides are used to deplete Xenopus embryos of mRNA encoding cyclin B protein, embryonic cleavage is inhibited. Surprisingly, after missing several rounds of cleavage, the cell cycle and cell division resumes. These studies indicate that the early embryonic cell cycle can proceed with undetectable levels of cyclin B encoding mRNA. In contrast, other events of normal development, including the activation of embryonic transcription and gastrulation, are inhibited." @default.
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• W1859347148 date "1991-04-01" @default.
• W1859347148 modified "2023-09-23" @default.
• W1859347148 title "Cyclin B mRNA depletion only transiently inhibits the <i>Xenopus</i> embryonic cell cycle" @default.
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• W1859347148 doi "https://doi.org/10.1242/dev.111.4.1173" @default.
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