Matches in SemOpenAlex for { <https://semopenalex.org/work/W1859596670> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W1859596670 endingPage "383" @default.
- W1859596670 startingPage "377" @default.
- W1859596670 abstract "A simple, rapid and validated method for separation and determination of mefloquine enantiomers was developed. Mefolquine was separated and quantitated on cyclodextrin chiral column Quest-CM carboxymethyl-BCD (250x4mm i.d., 5µm particle size) using a mixture of acetonitrile: 1% triethylammonium acetate buffer (pH = 4.5) (20:80 v∕ v) as a mobile phase at 20 o C and a flow rate of 1 mL /min. The UV-detector was set at 240 nm. The applied HPLC method allowed the separation and quantification of mefloquine enantiomers with good linearity (r < 0. 999) in the studied range. The relative standard deviations (RSD) were 0.865 and 0.907 for the mefloquine enantiomers with accuracy of 100.00 and 100.68. The limit of detection and limit of quantification of mefloquine enantionmers were found to be 5 and 15 µg/mL, respectively. The method was validated through the parameters of linearity, accuracy, precision and robustness. The HPLC method was applied for the quantitative determination of mefloquine in pharmaceutical formulations. Keywords Chiral separation, antimalarials, mefloquine, pharmaceutical analysis." @default.
- W1859596670 created "2016-06-24" @default.
- W1859596670 creator A5041501414 @default.
- W1859596670 creator A5073882188 @default.
- W1859596670 creator A5078065820 @default.
- W1859596670 creator A5079134670 @default.
- W1859596670 date "2012-04-17" @default.
- W1859596670 modified "2023-09-24" @default.
- W1859596670 title "A Validated HPLC Method for Separation and Determination of Mefloquine Enantiomers in Pharmaceutical Formulations" @default.
- W1859596670 hasPublicationYear "2012" @default.
- W1859596670 type Work @default.
- W1859596670 sameAs 1859596670 @default.
- W1859596670 citedByCount "1" @default.
- W1859596670 countsByYear W18595966702013 @default.
- W1859596670 crossrefType "journal-article" @default.
- W1859596670 hasAuthorship W1859596670A5041501414 @default.
- W1859596670 hasAuthorship W1859596670A5073882188 @default.
- W1859596670 hasAuthorship W1859596670A5078065820 @default.
- W1859596670 hasAuthorship W1859596670A5079134670 @default.
- W1859596670 hasConcept C119128265 @default.
- W1859596670 hasConcept C179998833 @default.
- W1859596670 hasConcept C185592680 @default.
- W1859596670 hasConcept C203014093 @default.
- W1859596670 hasConcept C2777199930 @default.
- W1859596670 hasConcept C2777425658 @default.
- W1859596670 hasConcept C2777463227 @default.
- W1859596670 hasConcept C2778048844 @default.
- W1859596670 hasConcept C43617362 @default.
- W1859596670 hasConcept C486523 @default.
- W1859596670 hasConcept C71240020 @default.
- W1859596670 hasConcept C71924100 @default.
- W1859596670 hasConceptScore W1859596670C119128265 @default.
- W1859596670 hasConceptScore W1859596670C179998833 @default.
- W1859596670 hasConceptScore W1859596670C185592680 @default.
- W1859596670 hasConceptScore W1859596670C203014093 @default.
- W1859596670 hasConceptScore W1859596670C2777199930 @default.
- W1859596670 hasConceptScore W1859596670C2777425658 @default.
- W1859596670 hasConceptScore W1859596670C2777463227 @default.
- W1859596670 hasConceptScore W1859596670C2778048844 @default.
- W1859596670 hasConceptScore W1859596670C43617362 @default.
- W1859596670 hasConceptScore W1859596670C486523 @default.
- W1859596670 hasConceptScore W1859596670C71240020 @default.
- W1859596670 hasConceptScore W1859596670C71924100 @default.
- W1859596670 hasIssue "2" @default.
- W1859596670 hasLocation W18595966701 @default.
- W1859596670 hasOpenAccess W1859596670 @default.
- W1859596670 hasPrimaryLocation W18595966701 @default.
- W1859596670 hasRelatedWork W1833190492 @default.
- W1859596670 hasRelatedWork W1918735424 @default.
- W1859596670 hasRelatedWork W1966730378 @default.
- W1859596670 hasRelatedWork W1997923714 @default.
- W1859596670 hasRelatedWork W2115244316 @default.
- W1859596670 hasRelatedWork W2130778328 @default.
- W1859596670 hasRelatedWork W2150442771 @default.
- W1859596670 hasRelatedWork W2184029542 @default.
- W1859596670 hasRelatedWork W2184440012 @default.
- W1859596670 hasRelatedWork W2333756386 @default.
- W1859596670 hasRelatedWork W2373150695 @default.
- W1859596670 hasRelatedWork W2409362245 @default.
- W1859596670 hasRelatedWork W2414329516 @default.
- W1859596670 hasRelatedWork W2590905216 @default.
- W1859596670 hasRelatedWork W2600323094 @default.
- W1859596670 hasRelatedWork W2794085105 @default.
- W1859596670 hasRelatedWork W2797318986 @default.
- W1859596670 hasRelatedWork W3083247704 @default.
- W1859596670 hasRelatedWork W2737482589 @default.
- W1859596670 hasRelatedWork W2741505461 @default.
- W1859596670 hasVolume "25" @default.
- W1859596670 isParatext "false" @default.
- W1859596670 isRetracted "false" @default.
- W1859596670 magId "1859596670" @default.
- W1859596670 workType "article" @default.