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• W1860789557 abstract "Deletions of specific DNA sequences are known to occur in Tetrahymena thermophila as a developmentally regulated process. Deletions of a particular region (region M) were previously shown to be of two alternative sizes, 0.6 or 0.9 kilobases (kb) (C.F. Austerberry, C.D. Allis, and M.-C. Yao, Proc. Natl. Acad. Sci. USA 81: 7383-7387). In this study, the nucleotide sequences for both deletions were determined. These two deletions share the same right junction, but their left junctions are 0.3 kb apart. An 8-base-pair (bp) sequence is present at both junctions of the 0.6-kb deletion, but only 5 bp of this direct repeat are present at the left junction of the 0.9-kb deletion. Further comparison revealed a common 10-bp sequence near each of the two left junctions and a similar sequence in inverted orientation near the right junction. These sequences may play a role in the developmental regulation of the deletion process." @default.
• W1860789557 created "2016-06-24" @default.
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• W1860789557 date "1988-09-01" @default.
• W1860789557 modified "2023-10-17" @default.
• W1860789557 title "Sequence structures of two developmentally regulated, alternative DNA deletion junctions in Tetrahymena thermophila." @default.
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• W1860789557 doi "https://doi.org/10.1128/mcb.8.9.3947" @default.
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