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- W1860974577 abstract "REVIOUS studies (DE SERRES 1956a) with a series of purple-adenine mutants in Piv eurospora crassa have demonstrated that these mutants can be divided into two groups on the basis of physiological (heterokaryon) and genetic (crossing) analyses. These studies indicated that the two groups arose from independent mutations a t two closely linked loci in the ad-3 region. The genetical analyses were based on random ascospore platings from intergroup crosses of adenine mutants carrying closely linked markers on both sides of the ad-3 region. In most instances, adenine-independent segregants were associated with a regular recombination of markers, suggesting that orthodox crossing over was taking place. However, in a few instances, exceptional adenine-independent segregants (with parental combinations of markers) were obtained. Because of these results, and in view of recent evidence for unorthodox segregation in tetrads of certain crosses in Neurospora (MITCHELL 1955a) and Saccharomyces (LINDEGREN 1955), it seemed desirable to perform a tetrad analysis on an intergroup cross of purple adenine mutants to determine whether the expected double mutant could be obtained, and whether tetrad segregations would prove to be regular in other respects." @default.
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- W1860974577 date "1957-09-01" @default.
- W1860974577 modified "2023-10-16" @default.
- W1860974577 title "STUDIES WITH PURPLE ADENINE MUTANTS IN NEUROSPORA CRASSA. II. TETRAD ANALYSES FROM A CROSS OF AN AD-3A MUTANT WITH AN AD-3B MUTANT" @default.
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- W1860974577 doi "https://doi.org/10.1093/genetics/42.5.608" @default.
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