FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1861192382> ?p ?o ?g. }

• W1861192382 abstract "In plant genomes, NB-LRR based resistance (R) genes tend to occur in clusters of variable size in a relatively small number of genomic regions. R-gene sequences mostly differentiate by accumulating point mutations and gene conversion events. Potato and tomato chromosome 4 harbours a syntenic R-gene locus (known as the R2 locus in potato) that has mainly been examined in central American/Mexican wild potato species on the basis of its contribution to resistance to late blight, caused by the oomycete pathogen Phytophthora infestans. Evidence to date indicates the occurrence of a fast evolutionary mode characterized by gene conversion events at the locus in these genotypes. A physical map of the R2 locus was developed for three Solanum tuberosum genotypes and used to identify the tomato syntenic sequence. Functional annotation of the locus revealed the presence of numerous resistance gene homologs (RGHs) belonging to the R2 gene family (R2GHs) organized into a total of 4 discrete physical clusters, three of which were conserved across S. tuberosum and tomato. Phylogenetic analysis showed clear orthology/paralogy relationships between S. tuberosum R2GHs but not in R2GHs cloned from Solanum wild species. This study confirmed that, in contrast to the wild species R2GHs, which have evolved through extensive sequence exchanges between paralogs, gene conversion was not a major force for differentiation in S. tuberosum R2GHs, and orthology/paralogy relationships have been maintained via a slow accumulation of point mutations in these genotypes. S. tuberosum and Solanum lycopersicum R2GHs evolved mostly through duplication and deletion events, followed by gradual accumulation of mutations. Conversely, widespread gene conversion is the major evolutionary force that has shaped the locus in Mexican wild potato species. We conclude that different selective forces shaped the evolution of the R2 locus in these lineages and that co-evolution with a pathogen steered selection on different evolutionary paths." @default.
• W1861192382 created "2016-06-24" @default.
• W1861192382 creator A5007633471 @default.
• W1861192382 creator A5016103258 @default.
• W1861192382 creator A5020428016 @default.
• W1861192382 creator A5043773070 @default.
• W1861192382 creator A5061330933 @default.
• W1861192382 creator A5072976408 @default.
• W1861192382 creator A5073869684 @default.
• W1861192382 creator A5082957132 @default.
• W1861192382 date "2015-10-24" @default.
• W1861192382 modified "2023-10-15" @default.
• W1861192382 title "A disease resistance locus on potato and tomato chromosome 4 exhibits a conserved multipartite structure displaying different rates of evolution in different lineages" @default.
• W1861192382 cites W1796126005 @default.
• W1861192382 cites W1925391342 @default.
• W1861192382 cites W1966649704 @default.
• W1861192382 cites W1969078664 @default.
• W1861192382 cites W1970581464 @default.
• W1861192382 cites W1970697531 @default.
• W1861192382 cites W1984966768 @default.
• W1861192382 cites W1987527386 @default.
• W1861192382 cites W1989581558 @default.
• W1861192382 cites W1995643110 @default.
• W1861192382 cites W1996640518 @default.
• W1861192382 cites W2012331775 @default.
• W1861192382 cites W2015458952 @default.
• W1861192382 cites W2048912867 @default.
• W1861192382 cites W2050821290 @default.
• W1861192382 cites W2052643756 @default.
• W1861192382 cites W2054396899 @default.
• W1861192382 cites W2057056172 @default.
• W1861192382 cites W2060517191 @default.
• W1861192382 cites W2079417483 @default.
• W1861192382 cites W2082909190 @default.
• W1861192382 cites W2103574752 @default.
• W1861192382 cites W2106882534 @default.
• W1861192382 cites W2109443190 @default.
• W1861192382 cites W2110135230 @default.
• W1861192382 cites W2110897106 @default.
• W1861192382 cites W2114659520 @default.
• W1861192382 cites W2118201962 @default.
• W1861192382 cites W2120556055 @default.
• W1861192382 cites W2120772351 @default.
• W1861192382 cites W2121096658 @default.
• W1861192382 cites W2133126366 @default.
• W1861192382 cites W2139134943 @default.
• W1861192382 cites W2140110977 @default.
• W1861192382 cites W2144932443 @default.
• W1861192382 cites W2146046531 @default.
• W1861192382 cites W2155611044 @default.
• W1861192382 cites W2161129570 @default.
• W1861192382 cites W2162069196 @default.
• W1861192382 cites W2163298865 @default.
• W1861192382 cites W2168644463 @default.
• W1861192382 cites W4241738169 @default.
• W1861192382 doi "https://doi.org/10.1186/s12870-015-0645-8" @default.
• W1861192382 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4619397" @default.
• W1861192382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26496718" @default.
• W1861192382 hasPublicationYear "2015" @default.
• W1861192382 type Work @default.
• W1861192382 sameAs 1861192382 @default.
• W1861192382 citedByCount "8" @default.
• W1861192382 countsByYear W18611923822017 @default.
• W1861192382 countsByYear W18611923822018 @default.
• W1861192382 countsByYear W18611923822019 @default.
• W1861192382 countsByYear W18611923822020 @default.
• W1861192382 countsByYear W18611923822021 @default.
• W1861192382 countsByYear W18611923822022 @default.
• W1861192382 crossrefType "journal-article" @default.
• W1861192382 hasAuthorship W1861192382A5007633471 @default.
• W1861192382 hasAuthorship W1861192382A5016103258 @default.
• W1861192382 hasAuthorship W1861192382A5020428016 @default.
• W1861192382 hasAuthorship W1861192382A5043773070 @default.
• W1861192382 hasAuthorship W1861192382A5061330933 @default.
• W1861192382 hasAuthorship W1861192382A5072976408 @default.
• W1861192382 hasAuthorship W1861192382A5073869684 @default.
• W1861192382 hasAuthorship W1861192382A5082957132 @default.
• W1861192382 hasBestOaLocation W18611923821 @default.
• W1861192382 hasConcept C104317684 @default.
• W1861192382 hasConcept C141231307 @default.
• W1861192382 hasConcept C182076605 @default.
• W1861192382 hasConcept C193252679 @default.
• W1861192382 hasConcept C2777257142 @default.
• W1861192382 hasConcept C2779999212 @default.
• W1861192382 hasConcept C2781083041 @default.
• W1861192382 hasConcept C2993140171 @default.
• W1861192382 hasConcept C53702515 @default.
• W1861192382 hasConcept C54355233 @default.
• W1861192382 hasConcept C5911399 @default.
• W1861192382 hasConcept C59822182 @default.
• W1861192382 hasConcept C7602840 @default.
• W1861192382 hasConcept C84597430 @default.
• W1861192382 hasConcept C86803240 @default.
• W1861192382 hasConcept C90132467 @default.
• W1861192382 hasConcept C93678976 @default.
• W1861192382 hasConceptScore W1861192382C104317684 @default.
• W1861192382 hasConceptScore W1861192382C141231307 @default.
• W1861192382 hasConceptScore W1861192382C182076605 @default.
• W1861192382 hasConceptScore W1861192382C193252679 @default.
• W1861192382 hasConceptScore W1861192382C2777257142 @default.

• next