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- W1861507055 abstract "The urinary excretion of tryptophan metabolites by growing swine was determined before and after the administration of 0.5 and 1.0 gm supplements of L-tryptophan. Kynurenine, 3-hydroxykynurenine, kynurenic acid and xanthurenic acid, which had been found major urinary metabolites of tryptophan in man, the dog and the rat proved to be minor metabolites of the amino acid in swine. The growing pigs excreted large quantities of Nα-acetylkynurenine, o-aminohippuric acid, anthranilic acid glucuronide and an unknown diazotizable amine. When swine were given supplements of tryptophan, no significant change was found in the urinary excretion of N-methyl-2-pyridone-5-carboxamide, although this metabolite appeared in relatively large quantities following the administration of 400 mg of nicotinamide." @default.
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- W1861507055 date "1960-01-01" @default.
- W1861507055 modified "2023-10-16" @default.
- W1861507055 title "Quantitative Studies on the Metabolites of Tryptophan in the Urine of Swine" @default.
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- W1861507055 doi "https://doi.org/10.1093/jn/70.1.21" @default.
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