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- W1861640504 abstract "Dendrotoxin is a snake polypeptide that blocks selectively and potently certain voltage-sensitive, fast-activating K+ channels in the nervous system, where it binds with high affinity to membranous acceptors. Herein, the acceptor protein for dendrotoxin in bovine synaptic membranes is solubilized in active form and its complete purification achieved by affinity chromatography, involving a novel elution procedure. This putative K+-channel constituent is shown to be a large oligomeric glycoprotein containing two major subunits, with Mr values of 75,000 and 37,000." @default.
- W1861640504 created "2016-06-24" @default.
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- W1861640504 date "1989-02-01" @default.
- W1861640504 modified "2023-10-14" @default.
- W1861640504 title "Dendrotoxin acceptor from bovine synaptic plasma membranes. Binding properties, purification and subunit composition of a putative constituent of certain voltage-activated K+ channels" @default.
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- W1861640504 doi "https://doi.org/10.1042/bj2570899" @default.
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