FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1861806188> ?p ?o ?g. }

• W1861806188 abstract "Introduction: Drug therapy in primary care is a broad field, with two areas previously identified as particularly challenging: treatment of the elderly and prescription of antibiotics against uncomplicated upper respiratory tract infections (URTIs). General practitioners’ (GPs’) attitudes and adherence to evidence-based treatment guidelines might be influenced by different interventions and need to be studied. Objectives: 1. To study different intervention models that might influence GPs’ adherence to treatment guidelines. 2. To describe GPs’ attitudes towards locally developed treatment guidelines.Methods: (Paper I) Systematic medication reviews by pharmacists were performed in a randomised controlled study of 369 elderly patients living in the community or nursing homes, who were using the multi-dose drug dispensing (MDD) system. Drug lists were assessed before and after the intervention with a focus on potentially inappropriate medications (PIMs). (Paper II) A retrospective analysis of medication lists was conducted in the same patient sample, with a focus on fall risk-increasing drugs (FRIDs), orthostatic drugs (ODs) and falls. (Paper III) A randomised controlled study was performed using two questionnaire-based behaviour change interventions aimed at reducing prescription of antibiotics against URTIs in primary care. (Paper IV) A qualitative study was performed using focus group interviews to assess GPs’ attitudes towards evidence-based local treatment guidelines.Results: Papers I and II: Systematic medication reviews by pharmacists reduced the number of patients taking PIMs and the total number of drugs these patients were taking, but not the number of patients taking more than three psychotropic drugs. A significant proportion (87%) of the study sample was taking FRIDs and ODs. Numbers of FRIDs were associated with the total number of drugs and with severe falls. There was no association between numbers of ODs and occurrence of severe falls. Paper III: There was a significant decrease in the antibiotic prescribing rate in one of the two intervention groups compared to the control group in patients 0-6 years, but no differences between the groups in patients of all ages. Paper IV: Trust in evidence-based recommendations and patient safety were found to be key factors in prescribing, as was the patient-doctor encounter, with emphasis on informing the patient. The GPs all experienced a lack of time to self-inform, difficulties managing patients with multiple prescribers and direct-to-consumer drug industry information. Cost containment was perceived as both a barrier and a motivator for adherence to guidelines.Conclusion: Multi-professional assessment of patient’s drug list and questionnaire-based behaviour change interventions might be feasible methods to improve quality of drug treatment in primary care and need to be studied further. GPs found trust in evidence-based guidelines and patient safety to be essential in drug prescribing." @default.
• W1861806188 created "2016-06-24" @default.
• W1861806188 creator A5069540033 @default.
• W1861806188 date "2014-01-01" @default.
• W1861806188 modified "2023-09-24" @default.
• W1861806188 title "Drug therapy - a challenge in primary care." @default.
• W1861806188 cites W1507048682 @default.
• W1861806188 cites W1515334277 @default.
• W1861806188 cites W1556031138 @default.
• W1861806188 cites W1584495192 @default.
• W1861806188 cites W1592215296 @default.
• W1861806188 cites W164609621 @default.
• W1861806188 cites W1757158931 @default.
• W1861806188 cites W1964140017 @default.
• W1861806188 cites W1966350418 @default.
• W1861806188 cites W1969308157 @default.
• W1861806188 cites W1969879564 @default.
• W1861806188 cites W1971480226 @default.
• W1861806188 cites W1972346076 @default.
• W1861806188 cites W1973019412 @default.
• W1861806188 cites W1979735814 @default.
• W1861806188 cites W1980002210 @default.
• W1861806188 cites W1984972420 @default.
• W1861806188 cites W1989730416 @default.
• W1861806188 cites W1991406862 @default.
• W1861806188 cites W1994239676 @default.
• W1861806188 cites W1997790484 @default.
• W1861806188 cites W2000147981 @default.
• W1861806188 cites W2000600940 @default.
• W1861806188 cites W2000882567 @default.
• W1861806188 cites W2001061068 @default.
• W1861806188 cites W2004074119 @default.
• W1861806188 cites W2006018047 @default.
• W1861806188 cites W2007108401 @default.
• W1861806188 cites W2007204234 @default.
• W1861806188 cites W2011357297 @default.
• W1861806188 cites W2013703587 @default.
• W1861806188 cites W2013765479 @default.
• W1861806188 cites W2014556601 @default.
• W1861806188 cites W2019687020 @default.
• W1861806188 cites W2019871639 @default.
• W1861806188 cites W2023000960 @default.
• W1861806188 cites W2027764308 @default.
• W1861806188 cites W2033792377 @default.
• W1861806188 cites W2038028146 @default.
• W1861806188 cites W2042947817 @default.
• W1861806188 cites W2049843830 @default.
• W1861806188 cites W2057906307 @default.
• W1861806188 cites W2060501510 @default.
• W1861806188 cites W2063117001 @default.
• W1861806188 cites W2063508762 @default.
• W1861806188 cites W2065661123 @default.
• W1861806188 cites W2067410131 @default.
• W1861806188 cites W2068596428 @default.
• W1861806188 cites W2073042971 @default.
• W1861806188 cites W2074130009 @default.
• W1861806188 cites W2074448530 @default.
• W1861806188 cites W2086743669 @default.
• W1861806188 cites W2089613546 @default.
• W1861806188 cites W2091843716 @default.
• W1861806188 cites W2092548209 @default.
• W1861806188 cites W2094113973 @default.
• W1861806188 cites W2098891980 @default.
• W1861806188 cites W2099697766 @default.
• W1861806188 cites W2101076802 @default.
• W1861806188 cites W2103759233 @default.
• W1861806188 cites W2104471440 @default.
• W1861806188 cites W2104971230 @default.
• W1861806188 cites W2105447127 @default.
• W1861806188 cites W2105950220 @default.
• W1861806188 cites W2107662268 @default.
• W1861806188 cites W2109827187 @default.
• W1861806188 cites W2110129090 @default.
• W1861806188 cites W2110919602 @default.
• W1861806188 cites W2111251477 @default.
• W1861806188 cites W2111892415 @default.
• W1861806188 cites W2113109156 @default.
• W1861806188 cites W2113597436 @default.
• W1861806188 cites W2117200901 @default.
• W1861806188 cites W2117318114 @default.
• W1861806188 cites W2117806419 @default.
• W1861806188 cites W2122328334 @default.
• W1861806188 cites W2124244861 @default.
• W1861806188 cites W2130338452 @default.
• W1861806188 cites W2130736933 @default.
• W1861806188 cites W2131256220 @default.
• W1861806188 cites W2134694831 @default.
• W1861806188 cites W2137053217 @default.
• W1861806188 cites W2140368570 @default.
• W1861806188 cites W2141211049 @default.
• W1861806188 cites W2142001242 @default.
• W1861806188 cites W2142225512 @default.
• W1861806188 cites W2143757630 @default.
• W1861806188 cites W2145413429 @default.
• W1861806188 cites W2147703536 @default.
• W1861806188 cites W2150985795 @default.
• W1861806188 cites W2151187436 @default.
• W1861806188 cites W2154362723 @default.
• W1861806188 cites W2154503433 @default.
• W1861806188 cites W2159372140 @default.

• next