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- W1862737253 abstract "A prenylated arylbenzofuran and six flavonoids were isolated from the fruits of Morus alba L. through silica gel, octadecyl silica gel, and Diaion HP-20 column chromatography. Based on the nuclear magnetic resonance, mass spectrometry, and infrared spectroscopic data, the chemical structures of the compounds were determined to be artoindonesianin O (1), isobavachalcone (2), morachalcone A (3), quercetin (4), astragalin (5), isoquercetin (6), and rutin (7). The isolated compounds were evaluated for protection of HT22-immortalized hippocampal cells against glutamate-induced oxidative stress. Compounds 1 and 3 exhibited protective effects with EC(50) values of 19.7±1.2 and 35.5±2.1 μM, respectively. The major compounds 1-3 and 7 were quantified using liquid chromatography/mass spectrometry analysis and were determined to be 1.88±2.1, 1.90±1.8, 0.78±1.5, and 37.29±2.2 mg/kg, respectively, in the ethanol extract of M. alba L. fruits." @default.
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- W1862737253 date "2015-04-01" @default.
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- W1862737253 title "Neuroprotective Effect of Prenylated Arylbenzofuran and Flavonoids from <i>Morus alba</i> Fruits on Glutamate-Induced Oxidative Injury in HT22 Hippocampal Cells" @default.
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- W1862737253 doi "https://doi.org/10.1089/jmf.2014.3196" @default.
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