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• W1863647524 abstract "Abstract Specification of the R7 photoreceptor cell in the developing Drosophila eye requires the seven in absentia (sina) gene. We demonstrate that ectopic expression of sina in all cells behind the morphogenetic furrow disrupts normal eye development during pupation, resulting in a severely disorganized adult eye. Earlier events of cell fate specification appear unaffected. A genetic screen for dominant enhancers and suppressors of this phenotype identified mutations in a number of genes required for normal eye development, including UbcD1, which encodes a ubiquitin conjugating enzyme; SR3-4a, a gene previously implicated in signaling downstream of Ras1; and a Drosophila homolog of the Sin3A transcriptional repressor." @default.
• W1863647524 created "2016-06-24" @default.
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• W1863647524 creator A5086255792 @default.
• W1863647524 date "1998-01-01" @default.
• W1863647524 modified "2023-10-16" @default.
• W1863647524 title "A Genetic Screen to Identify Components of the sina Signaling Pathway in Drosophila Eye Development" @default.
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• W1863647524 doi "https://doi.org/10.1093/genetics/148.1.277" @default.
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• W1863647524 hasPublicationYear "1998" @default.
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