Matches in SemOpenAlex for { <https://semopenalex.org/work/W1864359005> ?p ?o ?g. }
- W1864359005 endingPage "306" @default.
- W1864359005 startingPage "295" @default.
- W1864359005 abstract "Infection of naïve pregnant cows with non-cytopathic (ncp) bovine viral diarrhea virus (BVDV) results in transplacental infection of the fetus. Infection of the pregnant cow with ncp BVDV late in gestation (after day 150) results in transient infection (TI), as both the dam and fetus can mount an immune response to the virus. In contrast, if the fetus is infected with ncp BVDV early in gestation (before day 150), the fetal immune system is undeveloped and unable to recognize the virus as foreign. This results in induction of immune tolerance to the infecting BVDV strain and persistent infection (PI).Infection of naïve pregnant heifers with ncp BVDV2 on day 75 was hypothesized to induce differential gene expression in white blood cells of the dams and their fetuses, adversely affecting development and antiviral immune responses in PI fetuses.Gene expression differed in maternal blood cells in the presence of PI versus uninfected fetuses. PI adversely affected fetal development and antiviral responses, despite protective immune responses in the dam.Fetal PI with BVDV alters maternal immune function, compromises fetal growth and immune responses, and results in expression of maternal blood biomarkers that can be used to identify cows carrying PI fetuses." @default.
- W1864359005 created "2016-06-24" @default.
- W1864359005 creator A5001849175 @default.
- W1864359005 creator A5017608631 @default.
- W1864359005 creator A5027205500 @default.
- W1864359005 creator A5040745079 @default.
- W1864359005 creator A5055434163 @default.
- W1864359005 creator A5075696052 @default.
- W1864359005 date "2010-09-02" @default.
- W1864359005 modified "2023-10-16" @default.
- W1864359005 title "Maternal and Fetal Response to Fetal Persistent Infection with Bovine Viral Diarrhea Virus*" @default.
- W1864359005 cites W108005417 @default.
- W1864359005 cites W1895145922 @default.
- W1864359005 cites W1967074354 @default.
- W1864359005 cites W1967896668 @default.
- W1864359005 cites W1968313949 @default.
- W1864359005 cites W1970812281 @default.
- W1864359005 cites W1971690942 @default.
- W1864359005 cites W1976702065 @default.
- W1864359005 cites W1983602795 @default.
- W1864359005 cites W1988809996 @default.
- W1864359005 cites W1994543822 @default.
- W1864359005 cites W2002893363 @default.
- W1864359005 cites W2008119702 @default.
- W1864359005 cites W2016003471 @default.
- W1864359005 cites W2016402075 @default.
- W1864359005 cites W2018996246 @default.
- W1864359005 cites W2026908660 @default.
- W1864359005 cites W2028575270 @default.
- W1864359005 cites W2030423110 @default.
- W1864359005 cites W2032980461 @default.
- W1864359005 cites W2034724907 @default.
- W1864359005 cites W2035232812 @default.
- W1864359005 cites W2038818175 @default.
- W1864359005 cites W2041965572 @default.
- W1864359005 cites W2045862823 @default.
- W1864359005 cites W2046886534 @default.
- W1864359005 cites W2047877870 @default.
- W1864359005 cites W2050154239 @default.
- W1864359005 cites W2050361028 @default.
- W1864359005 cites W2050558417 @default.
- W1864359005 cites W2050701271 @default.
- W1864359005 cites W2058611372 @default.
- W1864359005 cites W2060962038 @default.
- W1864359005 cites W2062035204 @default.
- W1864359005 cites W2063671716 @default.
- W1864359005 cites W2068895548 @default.
- W1864359005 cites W2074717014 @default.
- W1864359005 cites W2076361525 @default.
- W1864359005 cites W2079702229 @default.
- W1864359005 cites W2081769332 @default.
- W1864359005 cites W2086601777 @default.
- W1864359005 cites W2086684874 @default.
- W1864359005 cites W2091137983 @default.
- W1864359005 cites W2093290398 @default.
- W1864359005 cites W2097393755 @default.
- W1864359005 cites W2103257088 @default.
- W1864359005 cites W2104144111 @default.
- W1864359005 cites W2106792156 @default.
- W1864359005 cites W2109971464 @default.
- W1864359005 cites W2117385209 @default.
- W1864359005 cites W2132748059 @default.
- W1864359005 cites W2141137217 @default.
- W1864359005 cites W2145906499 @default.
- W1864359005 cites W2146549512 @default.
- W1864359005 cites W2160063406 @default.
- W1864359005 cites W2185629202 @default.
- W1864359005 cites W2222888980 @default.
- W1864359005 cites W2314398811 @default.
- W1864359005 cites W27189400 @default.
- W1864359005 cites W4294107304 @default.
- W1864359005 cites W65867874 @default.
- W1864359005 cites W9014367 @default.
- W1864359005 doi "https://doi.org/10.1111/j.1600-0897.2010.00904.x" @default.
- W1864359005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20678166" @default.
- W1864359005 hasPublicationYear "2010" @default.
- W1864359005 type Work @default.
- W1864359005 sameAs 1864359005 @default.
- W1864359005 citedByCount "43" @default.
- W1864359005 countsByYear W18643590052012 @default.
- W1864359005 countsByYear W18643590052013 @default.
- W1864359005 countsByYear W18643590052014 @default.
- W1864359005 countsByYear W18643590052015 @default.
- W1864359005 countsByYear W18643590052016 @default.
- W1864359005 countsByYear W18643590052017 @default.
- W1864359005 countsByYear W18643590052018 @default.
- W1864359005 countsByYear W18643590052019 @default.
- W1864359005 countsByYear W18643590052020 @default.
- W1864359005 countsByYear W18643590052021 @default.
- W1864359005 countsByYear W18643590052022 @default.
- W1864359005 crossrefType "journal-article" @default.
- W1864359005 hasAuthorship W1864359005A5001849175 @default.
- W1864359005 hasAuthorship W1864359005A5017608631 @default.
- W1864359005 hasAuthorship W1864359005A5027205500 @default.
- W1864359005 hasAuthorship W1864359005A5040745079 @default.
- W1864359005 hasAuthorship W1864359005A5055434163 @default.
- W1864359005 hasAuthorship W1864359005A5075696052 @default.
- W1864359005 hasBestOaLocation W18643590051 @default.