Matches in SemOpenAlex for { <https://semopenalex.org/work/W1864894911> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1864894911 startingPage "2328" @default.
- W1864894911 abstract "Background: In pulmonary arterial hypertension increased HbA1c-levels reflect disease severity and have been identified as negative prognostic factors. HbA1c and their association with disease severity in operable chronic thromboembolic pulmonary hypertension (CTEPH) are unknown. Methods: HbA1c, hemodynamic and exercise parameters were prospectively analyzed in CTEPH before pulmonary endarterectomy (PEA). Using published criteria (American Diabetes Association), a HbA1c (International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)) 48 mmol/mol as manifest diabetes mellitus. All values are means ± standard deviation. Results: In 63 patients (BMI: 27.6 ± 5.6 kg/m2; age: 61 ± 12 years) with CTEPH (mean pulmonary arterial pressure :43.2 ± 11.2 mmHg, pulmonary vascular resistance: 662 ± 318 dyn*s/cm5, cardiac index (CI): 2.3 ± 0.6 l/min/m2, WHO Functional Class: 3.0 ± 0.6 and peak VO2: 12.1 ± 3.9 l/min/kg) the HbA1c-level was 40.5 ± 6.5 mmol/mol. Diabetes mellitus was observed in 9 patients (14 %) with a HbA1c-level of 53.6 ± 4.8 mmol/mol, whereas 22 patients (35 %) had glucose intolerance (HbA1c: 43.5 ± 1.9 mmol/mol). In univariate linear regression analysis elevated HbA1c-levels were associated with a reduced CI (r= -0.4, p= 0.001) and reduced peak VO 2 (r= -0.35, p= 0.005). Multivariate linear regression analysis including age, gender and BMI as covariates, confirmed HbA1c as independently correlated with CI (r= -0.4, p= 0.002) and peak VO 2 (r= -0.35, p= 0.02). Conclusions: In operable CTEPH diabetes mellitus and glucose intolerance assessed via HbA1c are common and associated with disease severity." @default.
- W1864894911 created "2016-06-24" @default.
- W1864894911 creator A5007818536 @default.
- W1864894911 creator A5022568677 @default.
- W1864894911 creator A5039785048 @default.
- W1864894911 creator A5046643474 @default.
- W1864894911 creator A5058797408 @default.
- W1864894911 creator A5075732001 @default.
- W1864894911 creator A5082907142 @default.
- W1864894911 creator A5087538996 @default.
- W1864894911 date "2014-09-01" @default.
- W1864894911 modified "2023-09-26" @default.
- W1864894911 title "HbA1c-levels in patients with operable chronic thromboembolic pulmonary hypertension" @default.
- W1864894911 hasPublicationYear "2014" @default.
- W1864894911 type Work @default.
- W1864894911 sameAs 1864894911 @default.
- W1864894911 citedByCount "0" @default.
- W1864894911 crossrefType "journal-article" @default.
- W1864894911 hasAuthorship W1864894911A5007818536 @default.
- W1864894911 hasAuthorship W1864894911A5022568677 @default.
- W1864894911 hasAuthorship W1864894911A5039785048 @default.
- W1864894911 hasAuthorship W1864894911A5046643474 @default.
- W1864894911 hasAuthorship W1864894911A5058797408 @default.
- W1864894911 hasAuthorship W1864894911A5075732001 @default.
- W1864894911 hasAuthorship W1864894911A5082907142 @default.
- W1864894911 hasAuthorship W1864894911A5087538996 @default.
- W1864894911 hasConcept C126322002 @default.
- W1864894911 hasConcept C134018914 @default.
- W1864894911 hasConcept C144301174 @default.
- W1864894911 hasConcept C164705383 @default.
- W1864894911 hasConcept C178853913 @default.
- W1864894911 hasConcept C2777428986 @default.
- W1864894911 hasConcept C2780221984 @default.
- W1864894911 hasConcept C2780930700 @default.
- W1864894911 hasConcept C38180746 @default.
- W1864894911 hasConcept C555293320 @default.
- W1864894911 hasConcept C58245268 @default.
- W1864894911 hasConcept C71924100 @default.
- W1864894911 hasConcept C84393581 @default.
- W1864894911 hasConceptScore W1864894911C126322002 @default.
- W1864894911 hasConceptScore W1864894911C134018914 @default.
- W1864894911 hasConceptScore W1864894911C144301174 @default.
- W1864894911 hasConceptScore W1864894911C164705383 @default.
- W1864894911 hasConceptScore W1864894911C178853913 @default.
- W1864894911 hasConceptScore W1864894911C2777428986 @default.
- W1864894911 hasConceptScore W1864894911C2780221984 @default.
- W1864894911 hasConceptScore W1864894911C2780930700 @default.
- W1864894911 hasConceptScore W1864894911C38180746 @default.
- W1864894911 hasConceptScore W1864894911C555293320 @default.
- W1864894911 hasConceptScore W1864894911C58245268 @default.
- W1864894911 hasConceptScore W1864894911C71924100 @default.
- W1864894911 hasConceptScore W1864894911C84393581 @default.
- W1864894911 hasLocation W18648949111 @default.
- W1864894911 hasOpenAccess W1864894911 @default.
- W1864894911 hasPrimaryLocation W18648949111 @default.
- W1864894911 hasRelatedWork W123840755 @default.
- W1864894911 hasRelatedWork W1516075295 @default.
- W1864894911 hasRelatedWork W1970291599 @default.
- W1864894911 hasRelatedWork W2007441899 @default.
- W1864894911 hasRelatedWork W2117013538 @default.
- W1864894911 hasRelatedWork W2130698880 @default.
- W1864894911 hasRelatedWork W2352756114 @default.
- W1864894911 hasRelatedWork W2357544821 @default.
- W1864894911 hasRelatedWork W2378165224 @default.
- W1864894911 hasRelatedWork W2392011128 @default.
- W1864894911 hasRelatedWork W2392678388 @default.
- W1864894911 hasRelatedWork W2891928825 @default.
- W1864894911 hasRelatedWork W2921440031 @default.
- W1864894911 hasRelatedWork W2970432689 @default.
- W1864894911 hasRelatedWork W3029229506 @default.
- W1864894911 hasRelatedWork W3030124352 @default.
- W1864894911 hasRelatedWork W3030134696 @default.
- W1864894911 hasRelatedWork W3031929629 @default.
- W1864894911 hasRelatedWork W3094481216 @default.
- W1864894911 hasRelatedWork W3211148523 @default.
- W1864894911 hasVolume "44" @default.
- W1864894911 isParatext "false" @default.
- W1864894911 isRetracted "false" @default.
- W1864894911 magId "1864894911" @default.
- W1864894911 workType "article" @default.