Matches in SemOpenAlex for { <https://semopenalex.org/work/W1864918053> ?p ?o ?g. }
- W1864918053 endingPage "462" @default.
- W1864918053 startingPage "441" @default.
- W1864918053 abstract "This chapter discusses the requirement of the cardiac neural crest cells in the formation of the septum that divides the cardiac arterial pole into systemic and pulmonary circulations. Further, cardiac neural crest cells directly support the normal development and patterning of derivatives of the caudal pharyngeal arches, including the great arteries and the thymus, thyroid, and parathyroids. Recently, cardiac neural crest cells have also been shown to indirectly influence the development of the secondary heart field, another derivative of the caudal pharynx, by modulating signaling in the pharynx. The contribution and function of the cardiac neural crest has been learned in avian models; most of the genes associated with cardiac neural crest function have been identified using mouse models. Together these studies show that the neural crest cells may not always directly cause abnormal cardiovascular development, but may be involved secondarily because they represent a major component in the complex tissue interactions in the caudal pharynx and outflow tract. Cardiac neural crest cells span from the caudal pharynx into the outflow tract, and therefore may be susceptible to any perturbation in or by other cells in these regions. Thus, understanding congenital cardiac outflow malformations in human sequences of malformations resulting from genetic and/or environmental insults necessarily requires understanding development of the cardiac neural crest." @default.
- W1864918053 created "2016-06-24" @default.
- W1864918053 creator A5075251120 @default.
- W1864918053 creator A5082425660 @default.
- W1864918053 date "2010-01-01" @default.
- W1864918053 modified "2023-10-18" @default.
- W1864918053 title "Role of Cardiac Neural Crest in the Development of the Caudal Pharyngeal Arches, the Cardiac Outflow and Disease" @default.
- W1864918053 cites W1264786469 @default.
- W1864918053 cites W1501608538 @default.
- W1864918053 cites W1510067290 @default.
- W1864918053 cites W1573772505 @default.
- W1864918053 cites W1730913150 @default.
- W1864918053 cites W1782272150 @default.
- W1864918053 cites W1882303649 @default.
- W1864918053 cites W1888616915 @default.
- W1864918053 cites W1892355381 @default.
- W1864918053 cites W1931060259 @default.
- W1864918053 cites W1937613866 @default.
- W1864918053 cites W1942976947 @default.
- W1864918053 cites W1948282121 @default.
- W1864918053 cites W1951705554 @default.
- W1864918053 cites W1955467086 @default.
- W1864918053 cites W1965032430 @default.
- W1864918053 cites W1970019361 @default.
- W1864918053 cites W1970063220 @default.
- W1864918053 cites W1971219444 @default.
- W1864918053 cites W1972371479 @default.
- W1864918053 cites W1972727772 @default.
- W1864918053 cites W1975513365 @default.
- W1864918053 cites W1976242688 @default.
- W1864918053 cites W1977346307 @default.
- W1864918053 cites W1977391705 @default.
- W1864918053 cites W1977978952 @default.
- W1864918053 cites W1978379566 @default.
- W1864918053 cites W1981628722 @default.
- W1864918053 cites W1982522478 @default.
- W1864918053 cites W1983026860 @default.
- W1864918053 cites W1983337287 @default.
- W1864918053 cites W1984691692 @default.
- W1864918053 cites W1984798293 @default.
- W1864918053 cites W1985921005 @default.
- W1864918053 cites W1986227171 @default.
- W1864918053 cites W1986320951 @default.
- W1864918053 cites W1987340200 @default.
- W1864918053 cites W1987460221 @default.
- W1864918053 cites W1989003609 @default.
- W1864918053 cites W1991690216 @default.
- W1864918053 cites W1993343256 @default.
- W1864918053 cites W1994142299 @default.
- W1864918053 cites W1994155034 @default.
- W1864918053 cites W1994622927 @default.
- W1864918053 cites W1996124672 @default.
- W1864918053 cites W1996433391 @default.
- W1864918053 cites W1997415972 @default.
- W1864918053 cites W1998066648 @default.
- W1864918053 cites W1998755974 @default.
- W1864918053 cites W1998892628 @default.
- W1864918053 cites W1999227500 @default.
- W1864918053 cites W2001339455 @default.
- W1864918053 cites W2002652075 @default.
- W1864918053 cites W2002732720 @default.
- W1864918053 cites W2003898883 @default.
- W1864918053 cites W2003959047 @default.
- W1864918053 cites W2004595614 @default.
- W1864918053 cites W2005776089 @default.
- W1864918053 cites W2006169009 @default.
- W1864918053 cites W2006417453 @default.
- W1864918053 cites W2006877541 @default.
- W1864918053 cites W2007116888 @default.
- W1864918053 cites W2007886643 @default.
- W1864918053 cites W2008685864 @default.
- W1864918053 cites W2011237068 @default.
- W1864918053 cites W2011790413 @default.
- W1864918053 cites W2014001268 @default.
- W1864918053 cites W2014399514 @default.
- W1864918053 cites W2016524823 @default.
- W1864918053 cites W2017054020 @default.
- W1864918053 cites W2018214043 @default.
- W1864918053 cites W2018826003 @default.
- W1864918053 cites W2020128838 @default.
- W1864918053 cites W2020233813 @default.
- W1864918053 cites W2020559241 @default.
- W1864918053 cites W2021171153 @default.
- W1864918053 cites W2021338904 @default.
- W1864918053 cites W2022265743 @default.
- W1864918053 cites W2022804978 @default.
- W1864918053 cites W2022853418 @default.
- W1864918053 cites W2024138944 @default.
- W1864918053 cites W2025087506 @default.
- W1864918053 cites W2026033093 @default.
- W1864918053 cites W2026462357 @default.
- W1864918053 cites W2027059131 @default.
- W1864918053 cites W2027173966 @default.
- W1864918053 cites W2027736032 @default.
- W1864918053 cites W2028512350 @default.
- W1864918053 cites W2030056242 @default.
- W1864918053 cites W2030752860 @default.
- W1864918053 cites W2031111711 @default.