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- W1866085729 abstract "Administration of additional estrogen reduced the latent period for mammary tumor induction following the implantation of estrone pellets, subcutaneously, in rats, but did not alter the course of established tumors. Testosterone, progesterone, or growth hormone increased the latent period and caused temporary regression of the established tumors. Oophorectomy, adrenalectomy, and hypophysectomy likewise affected tumor induction and tumor growth. Latent periods were prolonged, and a temporary reduction in tumor size occurred after oophorectomy or adrenalectomy. No mammary tumors developed in animals that were hypophysectomized before implantation of the estrone pellets, and permanent regression of tumors resulted when the operation was carried out after tumors had appeared." @default.
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- W1866085729 date "1964-08-01" @default.
- W1866085729 modified "2023-09-23" @default.
- W1866085729 title "ESTRONE-INDUCED MAMMARY TUMORS IN THE RAT. I. INDUCTION AND BEHAVIOR OF TUMORS." @default.
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