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- W1866434562 abstract "Background Children with congenital cytomegalovirus (CMV) infection face a bigger risk of neurological deficits and developmental delays associated with sensorineural hearing loss (SNHL). Their rehabilitation with a cochlear implant (CI) may therefore be inferior to the paediatric population in general. This study describes post-implant outcomes in children with CMV-related deafness and compares them to children with genetic deafness caused by GJB2 mutation (connexin 26) rehabilitated at the Centro Hospitalar e Universitário de Coimbra, Portugal. Material and Methods We conducted a revision of 11 children with profound hearing loss caused by congenital CMV infection rehabilitated with a CI in our institution. The children were divided into 3 groups according to age of implantation (<2 years, 2–3 years, >3 years) and their performance was compared to a group of children with genetic hearing loss caused by GJB2 mutation. To compare performance the following tests were applied: SIR, CAP, vocal characteristics evaluation grid (VCEG), MAIS, and MUSS. Results We found no differences between the two groups in terms of hearing thresholds obtained with a CI. In spite of a wider spread of results in the CMV group, there were no significant statistical differences in the SIR and VCEG tests or in the MAIS and MUSS questionnaires. There was a significant difference in the CAP test (p=0.049) where the GJB2 group had superior results. Conclusions The present study has shown that the CMV group had poorer results for the CAP test and a wider spread of results in the other tests. However, the CMV group attained results comparable to children with profound hearing loss and no other deficit, and benefited from rehabilitation with a cochlear implant." @default.
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- W1866434562 date "2015-06-30" @default.
- W1866434562 modified "2023-10-16" @default.
- W1866434562 title "RESULTS OF COCHLEAR IMPLANTATION IN CHILDREN WITH CONGENITAL CYTOMEGALOVIRUS INFECTION VERSUS GJB2 MUTATION" @default.
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- W1866434562 doi "https://doi.org/10.17430/892963" @default.
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