Matches in SemOpenAlex for { <https://semopenalex.org/work/W186706871> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W186706871 abstract "Oral drug administration is the most convenient method to administer drugs, particularly in the treatment of chronic diseases. This preference is generally the case, even when the site of drug action is beyond the gastrointestinal tract (GI), requiring the drug to be systemically available. For systemic drug availability, drug dosing via the oral route requires the drug to exhibit sufficient gastrointestinal absorption. Two components of drug absorption from solid oral-dosage forms (e.g., tablets, capsules) are: (1) drug dissolution from the dosage form, which results in the drug being in solution within the gut lumen, and (2) drug permeation across the GI wall. In this chapter, elements of GI drug permeability are discussed, with special emphasis on the enterocyte and the in vitro Caco-2 cell model. Included is a discussion of the lipid plasma membrane, in vitro drug permeability and its relation to in vivo permeability, and a discussion of future research directions." @default.
- W186706871 created "2016-06-24" @default.
- W186706871 creator A5044356220 @default.
- W186706871 creator A5070156157 @default.
- W186706871 creator A5073615016 @default.
- W186706871 date "2004-01-01" @default.
- W186706871 modified "2023-09-27" @default.
- W186706871 title "Human Intestinal Cellular Characteristics and Drug Permeability" @default.
- W186706871 cites W1486882165 @default.
- W186706871 cites W1494088772 @default.
- W186706871 cites W1499935265 @default.
- W186706871 cites W169609578 @default.
- W186706871 cites W1966960575 @default.
- W186706871 cites W1968535758 @default.
- W186706871 cites W1973312375 @default.
- W186706871 cites W1979196526 @default.
- W186706871 cites W2001562217 @default.
- W186706871 cites W2012906994 @default.
- W186706871 cites W2028358602 @default.
- W186706871 cites W2037230755 @default.
- W186706871 cites W2038606604 @default.
- W186706871 cites W2046827775 @default.
- W186706871 cites W2055645153 @default.
- W186706871 cites W2060191811 @default.
- W186706871 cites W2061554632 @default.
- W186706871 cites W2106448082 @default.
- W186706871 cites W2156321359 @default.
- W186706871 cites W2162601464 @default.
- W186706871 cites W2164752182 @default.
- W186706871 cites W217180910 @default.
- W186706871 cites W2187718168 @default.
- W186706871 cites W294850324 @default.
- W186706871 cites W4230139305 @default.
- W186706871 cites W4232529163 @default.
- W186706871 cites W8481647 @default.
- W186706871 doi "https://doi.org/10.1007/978-1-59259-745-1_10" @default.
- W186706871 hasPublicationYear "2004" @default.
- W186706871 type Work @default.
- W186706871 sameAs 186706871 @default.
- W186706871 citedByCount "2" @default.
- W186706871 countsByYear W1867068712015 @default.
- W186706871 crossrefType "book-chapter" @default.
- W186706871 hasAuthorship W186706871A5044356220 @default.
- W186706871 hasAuthorship W186706871A5070156157 @default.
- W186706871 hasAuthorship W186706871A5073615016 @default.
- W186706871 hasConcept C126322002 @default.
- W186706871 hasConcept C14029885 @default.
- W186706871 hasConcept C150903083 @default.
- W186706871 hasConcept C181389837 @default.
- W186706871 hasConcept C185592680 @default.
- W186706871 hasConcept C207001950 @default.
- W186706871 hasConcept C2777056448 @default.
- W186706871 hasConcept C2777882243 @default.
- W186706871 hasConcept C2779604457 @default.
- W186706871 hasConcept C2780035454 @default.
- W186706871 hasConcept C2781071285 @default.
- W186706871 hasConcept C2781430271 @default.
- W186706871 hasConcept C2992270614 @default.
- W186706871 hasConcept C41625074 @default.
- W186706871 hasConcept C55493867 @default.
- W186706871 hasConcept C71924100 @default.
- W186706871 hasConcept C77281830 @default.
- W186706871 hasConcept C86803240 @default.
- W186706871 hasConcept C98274493 @default.
- W186706871 hasConceptScore W186706871C126322002 @default.
- W186706871 hasConceptScore W186706871C14029885 @default.
- W186706871 hasConceptScore W186706871C150903083 @default.
- W186706871 hasConceptScore W186706871C181389837 @default.
- W186706871 hasConceptScore W186706871C185592680 @default.
- W186706871 hasConceptScore W186706871C207001950 @default.
- W186706871 hasConceptScore W186706871C2777056448 @default.
- W186706871 hasConceptScore W186706871C2777882243 @default.
- W186706871 hasConceptScore W186706871C2779604457 @default.
- W186706871 hasConceptScore W186706871C2780035454 @default.
- W186706871 hasConceptScore W186706871C2781071285 @default.
- W186706871 hasConceptScore W186706871C2781430271 @default.
- W186706871 hasConceptScore W186706871C2992270614 @default.
- W186706871 hasConceptScore W186706871C41625074 @default.
- W186706871 hasConceptScore W186706871C55493867 @default.
- W186706871 hasConceptScore W186706871C71924100 @default.
- W186706871 hasConceptScore W186706871C77281830 @default.
- W186706871 hasConceptScore W186706871C86803240 @default.
- W186706871 hasConceptScore W186706871C98274493 @default.
- W186706871 hasLocation W1867068711 @default.
- W186706871 hasOpenAccess W186706871 @default.
- W186706871 hasPrimaryLocation W1867068711 @default.
- W186706871 hasRelatedWork W1972932206 @default.
- W186706871 hasRelatedWork W2366105490 @default.
- W186706871 hasRelatedWork W2396656278 @default.
- W186706871 hasRelatedWork W2412629718 @default.
- W186706871 hasRelatedWork W2415873281 @default.
- W186706871 hasRelatedWork W3004322565 @default.
- W186706871 hasRelatedWork W4206379684 @default.
- W186706871 hasRelatedWork W4214815748 @default.
- W186706871 hasRelatedWork W4239132339 @default.
- W186706871 hasRelatedWork W2580680567 @default.
- W186706871 isParatext "false" @default.
- W186706871 isRetracted "false" @default.
- W186706871 magId "186706871" @default.
- W186706871 workType "book-chapter" @default.