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- W1868549501 abstract "A qualitative difference in response of various strains of aggregated mice to d -amphetamine was observed. Swiss-Webster mice exhibited the usual 8-fold or so difference in lethality to amphetamine between the isolated and aggregated situation. C57BL/6 mice exhibited a significant difference but was less than 2-fold. Unexpectedly, BDF1 and DBA/2 mice responded identically in the two situations. It was determined that the thresholds for pentylenetetrazol and for amphetamine were lowered for Swiss-Webster but not BDF1 mice in the aggregate situation.Quantitative differences between Swiss-Webster and BDF1 mice were observed as determined by lethality determinations, anticonvulsant effects and alterations of hexobarbital sleep times. Such quantitative differences were not unexpected.These results emphasize the need to specify in publications the strain of mice used in laboratory studies." @default.
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- W1868549501 date "1962-02-01" @default.
- W1868549501 modified "2023-09-27" @default.
- W1868549501 title "Strain difference in response of mice to d-amphetamine." @default.
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