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• W1869021630 abstract "Background: Standard colporraphy has been the main surgical procedure for vaginal wall prolapse for many years, with disappointing cure rates. Many investigators are now searching for alternative surgical techniques and materials to achieve better long term, postoperative results. Amniotic membrane is a natural human membrane tissue; when used as a vaginal graft, it will attract collagen, fibrinogen, and integrate with the local fascia providing a tough sheath, necessary for support and augmentation of the weak local fascia, to support the bladder, rectum, and vagina. It has been proven to demonstrate low antigenicity (incomplete HLA-A, B, C, and DR antigens), and hence will not be rejected by the recipient. Objective: To test the clinical and surgical applicability of using a biological fresh amniotic membrane graft for the trans-vaginal repair of site-specific defects in anterior and posterior vaginal wall prolapse. Method: A trapezoid shaped amniotic membrane graft (8 X12 cm) was applied to the anterior vaginal wall to correct the site-specific defect, by anchoring the graft to the Arcus Tendineous Fascia Pelvis, latterly at four points. While a superficial amniotic membrane graft (8 X 4cm) was placed on the posterior vaginal wall, between the rectum and the vagina, to correct the posterior wall defect. Excess graft material was excised. 21 patients had this procedure till now. All had spinal anesthesia, *3 had it with a vaginal hysterectomy, *6 had it with an anterior & posterior vaginal repair, *12 had it with a posterior vaginal repair. Results: Patients with grade II or III vaginal defects were included in this study i. *Average age was 44.6 years. ii. *Average parity was 4.2. iii. *80% of patients had no complications, 20% had minor complications, relieved by medication. iv. *No serious infections, rejections, and complications were noted till now (Max. period of study-180 days) v. *3 had mild de novo urgency. vi. *1 had delayed vaginal healing. Conclusion: In our study amniotic membrane graft was used for treating vaginal wall defects successfully with no serious complications. We feel that more studies are needed to better evaluate the efficacy and safety of this new surgical technique for vaginal wall repairs." @default.
• W1869021630 created "2016-06-24" @default.
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• W1869021630 date "2015-09-01" @default.
• W1869021630 modified "2023-09-26" @default.
• W1869021630 title "Vaginal Wall Repair – Using Amniotic Membrane Graft" @default.
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• W1869021630 doi "https://doi.org/10.15406/ogij.2015.2.00056" @default.
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