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- W1869191601 abstract "The uroepithelium lines the inner surface of the renal pelvis, the ureters, and the urinary bladder, where it forms a tight barrier that allows for retention of urine, while preventing the unregulated movement of ions, solutes, and toxic metabolites across the epithelial barrier. In the case of the bladder, the permeability barrier must be maintained even as the organ undergoes cyclical changes in pressure as it fills and empties. Beyond furthering our understanding of barrier function, new analysis of the uroepithelium is providing information about how detergent-insoluble membrane/protein domains called plaques are formed at the apical plasma membrane of the surface umbrella cells, how mechanical stimuli such as pressure alter exocytic and endocytic traffic in epithelial cells such as umbrella cells, and how changes in pressure are communicated to the underlying nervous system." @default.
- W1869191601 created "2016-06-24" @default.
- W1869191601 creator A5084438326 @default.
- W1869191601 date "2003-12-09" @default.
- W1869191601 modified "2023-10-11" @default.
- W1869191601 title "The Uroepithelium: Not Just a Passive Barrier" @default.
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- W1869191601 doi "https://doi.org/10.1046/j.1600-0854.2003.00156.x" @default.
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