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• W1870356487 abstract "The objective of this study was to investigate the photobiological responses of the haloalkaliphilic euryarchaeon Natronomonas pharaonis to environmentally relevant polychromatic UV radiation, simulating either the present UV radiation climate (λ>290 nm) or that of the early Earth (λ>220 nm), and to monochromatic UVC radiation (λ=254 nm) for comparison with the literature data. UV-induced bipyrimidine DNA photoproducts were determined using a sensitive and accurate HPLC tandem mass spectrometry assay, allowing to identify and quantify each type of photoproducts formed in the DNA of a UV-irradiated halophilic archaeon. The thymine cytosine (TC) pyrimidine (6-4) pyrimidone photoproduct and the TC cyclobutane pyrimidine dimer accounted for almost 80% of the total induced DNA photolesions, regardless of the wavelength range tested. These prominent formation rates of TC photoproducts correlated with the genomic frequencies of TC dinucleotides in N. pharaonis." @default.
• W1870356487 created "2016-06-24" @default.
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• W1870356487 date "2010-04-23" @default.
• W1870356487 modified "2023-09-25" @default.
• W1870356487 title "UV photoreactions of the extremely haloalkaliphilic euryarchaeon Natronomonas pharaonis" @default.
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• W1870356487 doi "https://doi.org/10.1111/j.1574-6941.2010.00893.x" @default.
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